3129652-66-7
3129652-66-7
Chemical Structure
TMEM175 agonist 3
- CAS No.: 3129652-66-7
- Formula:C24H21N5O4S
- Molecular Weight:475.52
InChIKey: FDVHDJALJNRGBZ-JOCHJYFZSA-N
SMILES: O=C1N(NS(C2=CC3=C(C=CN3)C=C2)(=O)=O)C([C@@H](C4=CC=CC=C4)OC)=NC5=C1C=CN=C5C
Biological Activity: TMEM175 agonist 3 (Compound 123) is a TMEM175 agonist, with an EC50 of 0.044 μM in human TMEM175 FLIPR assays and an EC50 of 0.073 μM in human TMEM175 EP assays. TMEM175 agonist 3 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases[1].
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TMEM175 agonist 3 | TMEM175 agonist 3 (Compound 123) is a TMEM175 agonist, with an EC50 of 0.044 μM in human TMEM175 FLIPR assays and an EC50 of 0.073 μM in human TMEM175 EP assays. TMEM175 agonist 3 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases. | |||||||||||||||||||||
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References
Keywords
