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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
human renin
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "human renin" in MCE Product Catalog:
248
248 Publications Verification
Synonyms: Angiotensin II; Ang II; DRVYIHPF
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248
248 Publications Verification
Synonyms: Angiotensin II acetate; Ang II acetate; DRVYIHPF acetate
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Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
248
248 Publications Verification
Synonyms: Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA
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2
2 Cited Publications
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LY2886721 is a potent, selective and orally active beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 20.3 nM for recombinant human BACE1. LY2886721 is selectivity against cathepsin D, pepsin, and renin, but lacking selectivity against BACE2 (IC50 of 10.2 nM). LY2886721 can across blood-brain barrier and has the potential for Alzheimer's disease treatment .
2
2 Cited Publications
Cat. No.: HY-B0384
CAS No.: 110221-44-8
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Temocapril hydrochloride is an orally active angiotensin-converting enzyme (ACE) inhibitor. Temocapril hydrochloride can be used for the research of hypertension, congestive heart failure, acute myocardial infarction, insulin resistance, and renal diseases .
2
2 Cited Publications
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Temocapril is an orally active angiotensin-converting enzyme (ACE) inhibitor. Temocapril can be used for the research of hypertension, congestive heart failure, acute myocardial infarction, insulin resistance, and renal diseases .
Synonyms: E-3174; EXP-3174
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Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure .
Synonyms: E-3174 d4; EXP-3174 d4
Cat. No.: HY-P1486
CAS No.: 104180-23-6
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Cat. No.: HY-P5123A
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Cat. No.: HY-13948BS
Purity: 98.11%
Synonyms: Angiotensin II-13C6,15N TFA; Ang II-13C6,15N TFA; DRVY(I-13C6,15N)HPF TFA
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Cat. No.: HY-P5939
CAS No.: 82048-97-3
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Cat. No.: HY-105205
CAS No.: 119625-78-4
Synonyms: CP-80,794
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Terlakiren (CP-80,794) is an orally active inhibitor of renin. Terlakiren inhibits the efficacy of human renin with an IC50 value of 0.7 nM. Terlakiren has potential applications in hypertension .
Cat. No.: HY-A0184
CAS No.: 126222-34-2
Synonyms: Ro 42-5892; Ro 42-5892/001
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Remikiren (Ro 42-5892) is an orally active and highly specific renin inhibitor. Remikiren specifically inhibits human reninand human plasma renin with IC50 values of 0.7 and 0.8 nM, respectively. Remikiren also reduces mean arterial blood pressure in sodium-depleted marmosets and squirrel monkeys. Remikiren can be used in study of hypertension .
Cat. No.: HY-105503
CAS No.: 138447-68-4
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SQ 33800 is a potent inhibitor of human renin with an IC50 of 0.35 nM. SQ 33800 can be used for the research of cardiovascular disease .
Cat. No.: HY-177329
CAS No.: 123300-09-4
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U80215, a dansylated peptide, is a competitive human renin inhibitor with the IC50 of 2.3 μM. U80215 shows excitation and emission maxima at 340 and 530 nm .
Cat. No.: HY-109034A
CAS No.: 1202269-24-6
Synonyms: AK-272; SCO-272
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Imarikiren hydrochloride (AK-272) is an orally active, selective Renin inhibitor with an IC50 value of 2.1 nM against h-Renin. Imarikiren hydrochloride blocks the conversion of Angiotensinogen to Angiotensin I and reduces mean arterial pressure by inhibiting Angiotensin II that binds to AT1. Imarikiren hydrochloride alleviates myocardial hypertrophy and pulmonary congestion, exerting cardioprotective effects. Imarikiren hydrochloride can be used in research related to hypertension and heart failure .
Cat. No.: HY-P2492
CAS No.: 142988-22-5
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Cat. No.: HY-P1486A
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Cat. No.: HY-P4891
CAS No.: 136865-09-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
