8 Results for "

hyphal damage

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "hyphal damage" in MCE Product Catalog:

Cat. No.: HY-N6784
CAS No.: 11050-94-5
Oligomycin B is an antibiotic that acts as a non-selective inhibitor of ATP Synthase. Oligomycin B increases mitochondrial membrane potential. Oligomycin B induces apoptosis and necrosis. Oligomycin B impairs the motility of Plasmopara viticola zoospores and induces their lysis. Oligomycin B inhibits Magnaporthe oryzae (wheat blast fungus) and suppresses the development of wheat blast. Oligomycin B reduces hyphal growth and spore germination of Botrytis cinerea, and protects Arabidopsis thaliana against Botrytis cinerea infection. Oligomycin B exacerbates cytotoxic brain edema in rats with cerebral cortical contusion, increases intracranial pressure and brain water content, and aggravates mitochondrial damage in these rats. Oligomycin B is used in studies related to grape downy mildew, traumatic brain injury, wheat blast, and gray mold .
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Cat. No.: HY-N2558
CAS No.: 19668-69-0
Murrayone is a coumarin compound with antifungal and antiplatelet activities. Murrayone disrupts fungal redox homeostasis, impairs cell membrane integrity, inhibits sporulation, spore germination and hyphal growth, and causes morphological damage to fungal cells. Murrayone reduces the disease severity of blueberry fruits infected with Botrytis cinerea. Murrayone can be used in studies related to fungal infections and vascular diseases .
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Cat. No.: HY-169202
CAS No.: 3055029-65-4
Target:  

Fungal

Research Areas:  

Infection

Antifungal agent 118 (compund C22) inhibits the hyphal growth of V. mali by inducing oxidative damage and disrupting the integrity of the cell membrane .
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Cat. No.: HY-168042
Target:  

Bacterial Fungal

Research Areas:  

Infection

Antibacterial agent 243 is an antibacterial agent, with EC50 values of 0.64 mg/L for Valsa mali, 26 mg/L for allicin, and 0.33 mg/L for tebuconazole. Antibacterial agent 243 can induce hyphal shrinkage and collapse, trigger the accumulation of reactive oxygen species inside cells, regulate antioxidant enzyme activity, initiate lipid peroxidation, and ultimately cause irreversible oxidative damage to Valsa mali cells .
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Cat. No.: HY-187509
Research Areas:  

Infection

Succinate dehydrogenase-IN-13 is a succinate dehydrogenase inhibitor with an IC50 of 8.69 μM against Rhizoctonia solani. Succinate dehydrogenase-IN-13 binds stably within the succinate dehydrogenase active site to disrupt fungal respiration and energy metabolism, and induces hyphal distortion and mitochondrial damage in Rhizoctonia solani. Succinate dehydrogenase-IN-13 reduces intracellular ATP levels in Rhizoctonia solani mycelia. Succinate dehydrogenase-IN-13 can be used for the research of Rhizoctonia solani infection, Botrytis cinerea infection .
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Cat. No.: HY-184308
CAS No.: 3123321-73-0
Research Areas:  

Infection

Antifungal agent-165 is an antifungal agent with in vitro activity against Rhizoctonia solani. Antifungal agent-165 inhibits catalase (CAT) activity, drives intracellular ROS accumulation, and induces oxidative damage. Antifungal agent-165 disrupts fungal hyphal morphology, compromises cell membrane integrity, and triggers cellular content leakage in Rhizoctonia solani. Antifungal agent-165 can be used for the research of potato black scurf disease .
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Cat. No.: HY-W102893
CAS No.: 99910-50-6
4,6-Dibromo indole is a natural product found in the adipose tissue of bottlenose dolphins, algae, and invertebrates including species of the genus Tubastrea, with multiple activities such as nematicidal and antifungal properties. 4,6-Dibromo indole inhibits the motility of Caenorhabditis elegans and induces a multi-stage nematicidal effect. 4,6-Dibromo indole inhibits the growth, biofilm formation, and yeast-hypha transition of Candida, induces ROS accumulation, disrupts hyphal networks, and reduces biofilm biomass. 4,6-Dibromo indole can be used in studies on crop damage related to nematode infestation and Candida infection .
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Cat. No.: HY-183722
Research Areas:  

Infection

SDH-IN-46 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 1.21 μM. SDH-IN-46 disrupts fungal respiration via mitochondrial respiratory chain enzyme targeting and exhibits broad-spectrum antifungal activity. SDH-IN-46 exhibits substantial protective effects against S. sclerotiorum on oilseed rape leaves, Rhizoctonia solani on rice leaves, and Valsa mali on apple fruits .
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