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indigo

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By Targets:	Apoptosis (4) COX (2) Environmental Pollutants (1) Fluorescent Dye (8) Interleukin Related (2) Leukotriene Receptor (2) NF-κB (2) NO Synthase (2) Phosphatase (1) Reference Standards (5) TNF Receptor (2)
By Research Areas:	Cancer (10) Inflammation/Immunology (3) Metabolic Disease (1)

Inhibitors & Agonists

Fluorescent Dyes

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0117

Indirubin Maximum Cited Publications 12 Publications Verification Couroupitine B; indigo red; indigopurpurin	Apoptosis	Cancer
Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .

HY-W040226

Indigo carmine indigotindisulfonate sodium; C.I.Acid Blue 74	Environmental Pollutants Fluorescent Dye	Cancer
Indigo carmine is an efficient reagent for the determination of ozone by chemlluminescence (CL) .

HY-N0335

*Indigo* 1 Publications Verification	Fluorescent Dye	Others
Indigo is a blue dye. Indigo stains cellulose fibers such as cotton. Indigo stains food or biological samples to visualize and quantify the uptake or distribution of substances by organisms .

HY-N6607

Tryptanthrin 5+ Cited Publications	Leukotriene Receptor NO Synthase NF-κB COX TNF Receptor Interleukin Related	Inflammation/Immunology Cancer
Tryptanthrin is an indole quinazoline that could be an alkaloid from indigo-bearing plants. Tryptanthrin is a potent and orally active cellular Leukotriene (LT) biosynthesis inhibitor. Tryptanthrin has anticancer activity. Tryptanthrin suppresses the expression levels of NOS1, COX-2, and NF-κB and regulates the expression levels of IL-2, IL-10, and TNF-α .

HY-107869

Isoindigo	Fluorescent Dye	Cancer
Isoindigo acts as the acceptor unit in donor-acceptor (D-A) conjugated polymers and belongs to the indigo dye family. Isoindigo contains two lactam rings and exhibits strong electron-withdrawing properties. Isoindigo can be used in dyeing and pigment preparation. Isoindigo shows high mobility and excellent environmental stability in field-effect transistors (FETs). Isoindigo possesses the activity to inhibit tumor cell proliferation and has certain anti-tumor activity .

HY-N0117A

(Z)-Indirubin (Z)-Couroupitine B; (Z)-indigo red; (Z)-indigopurpurin	Apoptosis	Cancer
(Z)-Indirubin is an isomer of Indirubin (HY-N0117). Indirubin is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .

HY-N0117AR

(Z)-Indirubin (Standard) (Z)-Couroupitine B (Standard); (Z)-indigo red (Standard); (Z)-indigopurpurin (Standard)	Reference Standards Apoptosis	Cancer
(Z)-Indirubin (Standard) is the analytical standard of (Z)-Indirubin (HY-N0117A). (Z)-Indirubin is an isomer of Indirubin (HY-N0117). Indirubin is a bisindole alkaloid with significant anticancer activity against chronic myeloid leukemia.

HY-N6607R

Tryptanthrin (Standard)	Reference Standards Leukotriene Receptor NO Synthase NF-κB COX TNF Receptor Interleukin Related	Inflammation/Immunology Cancer
Tryptanthrin (Standard) is the analytical standard of Tryptanthrin. This product is intended for research and analytical applications. Tryptanthrin is an indole quinazoline that could be an alkaloid from indigo-bearing plants. Tryptanthrin is a potent and orally active cellular Leukotriene (LT) biosynthesis inhibitor. Tryptanthrin has anticancer activity. Tryptanthrin suppresses the expression levels of NOS1, COX-2, and NF-κB and regulates the expression levels of IL-2, IL-10, and TNF-α .

HY-D1195

Vat Blue 2	Fluorescent Dye	Others
Vat Blue 2, a indigo (HY-N0335) derivative, is a dark blue 5,5'-dibromo-4,4'-dichloroindigo dye .

HY-N0117R

Indirubin (Standard) Couroupitine B (Standard); indigo red (Standard); indigopurpurin (Standard)	Reference Standards Apoptosis	Cancer
Indirubin (Standard) is the analytical standard of Indirubin. This product is intended for research and analytical applications. Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .

HY-W040226R

Indigo carmine (Standard) indigotindisulfonate sodium (Standard); C.I.Acid Blue 74 (Standard)	Fluorescent Dye Reference Standards	Cancer
Indigo carmine (Standard) is the analytical standard of Indigo carmine. This product is intended for research and analytical applications. Indigo carmine is an efficient reagent for the determination of ozone by chemlluminescence (CL) .

HY-W009458

3-Indoxyl phosphate sodium 3-IP sodium	Phosphatase	Metabolic Disease
3-Indoxyl phosphate (3-IP) is a chromogenic and electrochemical substrate for alkaline phosphatase. Upon enzymatic cleavage by alkaline phosphatase, 3-indoxyl is released and subsequently oxidized to produce water-insoluble indigo, which can be quantified by colorimetric detection at 660 nm as a measure of alkaline phosphatase activity. 3-Indoxyl phosphate can also be converted to water-soluble leucoindigo by reduction of indigo in alkaline solution by sodium dithionite, which can be quantified by colorimetric detection at 415 nm or voltametric detection as a measure of alkaline phosphatase activity.2 3-Indoxyl phosphate has been used in ELISAs.

HY-W154295

Purple-β-D-Gal	Fluorescent Dye	Others
Purple-β-D-Gal is a chromogenic β-galactosidase substrate. Intracellular enzymatic hydrolysis of Purple-β-D-Gal generates free indoxyl molecules, which undergo in situ oxidation and subsequent dimerization to produce chromogenic, water-insoluble, indigo precipitates. Purple-β-D-Gal can be used for the detection of β-galactosidase activity .

HY-W011422

2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone NSC 528	Fluorescent Dye	Others
2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone (NSC 528) is a colorimetric dye used for the detection of phenolic compounds. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone reacts with phenolic compounds at a pH of about 9.4 to produce an indigo dye. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone has been used as a Gibbs reagent for the colorimetric detection of phenolic compounds. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone has also been used in a colorimetric reaction for the quantitative colorimetric detection of aflatoxins, turning the colorless aflatoxins green with an absorption band at 673 nm.

HY-N12481

Cephalandole B	Others	Inflammation/Immunology
Cephalandole B is an indigo alkaloid that has the activity of inhibiting IL-17A gene expression. Cephalandole B significantly inhibited the activity of IL-17A luciferase reporter gene in Jukat cells, and this inhibitory effect was dose-dependent. Cephalandole B may have important application prospects in inflammation-related research .

HY-107869R

Isoindigo (Standard)	Reference Standards Fluorescent Dye	Cancer
Isoindigo (Standard) is the analytical standard of Isoindigo (HY-107869). This product is intended for research and analytical applications. Isoindigo acts as the acceptor unit in donor-acceptor (D-A) conjugated polymers and belongs to the indigo dye family. Isoindigo contains two lactam rings and exhibits strong electron-withdrawing properties. Isoindigo can be used in dyeing and pigment preparation. Isoindigo shows high mobility and excellent environmental stability in field-effect transistors (FETs). Isoindigo possesses the activity to inhibit tumor cell proliferation and has certain anti-tumor activity .

Cat. No.	Product Name	Type

HY-W040226

Indigo carmine indigotindisulfonate sodium; C.I.Acid Blue 74	Fluorescent Dyes
Indigo carmine is an efficient reagent for the determination of ozone by chemlluminescence (CL) .

HY-N0335

*Indigo* 1 Publications Verification	Fluorescent Dyes
Indigo is a blue dye. Indigo stains cellulose fibers such as cotton. Indigo stains food or biological samples to visualize and quantify the uptake or distribution of substances by organisms .

HY-D1195

Vat Blue 2	Fluorescent Dyes
Vat Blue 2, a indigo (HY-N0335) derivative, is a dark blue 5,5'-dibromo-4,4'-dichloroindigo dye .

HY-W040226R

Indigo carmine (Standard) indigotindisulfonate sodium (Standard); C.I.Acid Blue 74 (Standard)	Fluorescent Dyes
Indigo carmine (Standard) is the analytical standard of Indigo carmine. This product is intended for research and analytical applications. Indigo carmine is an efficient reagent for the determination of ozone by chemlluminescence (CL) .

HY-W009458

3-Indoxyl phosphate sodium 3-IP sodium	Fluorescent Dyes
3-Indoxyl phosphate (3-IP) is a chromogenic and electrochemical substrate for alkaline phosphatase. Upon enzymatic cleavage by alkaline phosphatase, 3-indoxyl is released and subsequently oxidized to produce water-insoluble indigo, which can be quantified by colorimetric detection at 660 nm as a measure of alkaline phosphatase activity. 3-Indoxyl phosphate can also be converted to water-soluble leucoindigo by reduction of indigo in alkaline solution by sodium dithionite, which can be quantified by colorimetric detection at 415 nm or voltametric detection as a measure of alkaline phosphatase activity.2 3-Indoxyl phosphate has been used in ELISAs.

3-Indoxyl phosphate sodium

3-IP sodium

Fluorescent Dyes

3-Indoxyl phosphate (3-IP) is a chromogenic and electrochemical substrate for alkaline phosphatase. Upon enzymatic cleavage by alkaline phosphatase, 3-indoxyl is released and subsequently oxidized to produce water-insoluble indigo, which can be quantified by colorimetric detection at 660 nm as a measure of alkaline phosphatase activity. 3-Indoxyl phosphate can also be converted to water-soluble leucoindigo by reduction of indigo in alkaline solution by sodium dithionite, which can be quantified by colorimetric detection at 415 nm or voltametric detection as a measure of alkaline phosphatase activity.2 3-Indoxyl phosphate has been used in ELISAs.

HY-W154295

Purple-β-D-Gal	Fluorescent Dyes
Purple-β-D-Gal is a chromogenic β-galactosidase substrate. Intracellular enzymatic hydrolysis of Purple-β-D-Gal generates free indoxyl molecules, which undergo in situ oxidation and subsequent dimerization to produce chromogenic, water-insoluble, indigo precipitates. Purple-β-D-Gal can be used for the detection of β-galactosidase activity .

HY-W011422

2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone NSC 528	Fluorescent Dyes
2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone (NSC 528) is a colorimetric dye used for the detection of phenolic compounds. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone reacts with phenolic compounds at a pH of about 9.4 to produce an indigo dye. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone has been used as a Gibbs reagent for the colorimetric detection of phenolic compounds. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone has also been used in a colorimetric reaction for the quantitative colorimetric detection of aflatoxins, turning the colorless aflatoxins green with an absorption band at 673 nm.

2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone

NSC 528

Fluorescent Dyes

2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone (NSC 528) is a colorimetric dye used for the detection of phenolic compounds. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone reacts with phenolic compounds at a pH of about 9.4 to produce an indigo dye. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone has been used as a Gibbs reagent for the colorimetric detection of phenolic compounds. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone has also been used in a colorimetric reaction for the quantitative colorimetric detection of aflatoxins, turning the colorless aflatoxins green with an absorption band at 673 nm.

Indirubin Maximum Cited Publications 12 Publications Verification Couroupitine B; indigo red; indigopurpurin	Alkaloids other families Classification of Application Fields Plants Disease Research Fields Indole Alkaloids Source Classification Cancer	Apoptosis
Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .

*Indigo* 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Leguminosae Indigofera tinctoria Linn. Plants Disease Research Fields Cancer	Fluorescent Dye
Indigo is a blue dye. Indigo stains cellulose fibers such as cotton. Indigo stains food or biological samples to visualize and quantify the uptake or distribution of substances by organisms .

Tryptanthrin 5+ Cited Publications	Alkaloids Classification of Application Fields Polygonaceae Plants Polygonum tinctorium Ait. Inflammation/Immunology Disease Research Fields Indole Alkaloids Source Classification	Leukotriene Receptor NO Synthase NF-κB COX TNF Receptor Interleukin Related
Tryptanthrin is an indole quinazoline that could be an alkaloid from indigo-bearing plants. Tryptanthrin is a potent and orally active cellular Leukotriene (LT) biosynthesis inhibitor. Tryptanthrin has anticancer activity. Tryptanthrin suppresses the expression levels of NOS1, COX-2, and NF-κB and regulates the expression levels of IL-2, IL-10, and TNF-α .

Tryptanthrin (Standard)	Alkaloids Structural Classification Polygonaceae Plants Polygonum tinctorium Ait. Indole Alkaloids Source Classification	Reference Standards Leukotriene Receptor NO Synthase NF-κB COX TNF Receptor Interleukin Related
Tryptanthrin (Standard) is the analytical standard of Tryptanthrin. This product is intended for research and analytical applications. Tryptanthrin is an indole quinazoline that could be an alkaloid from indigo-bearing plants. Tryptanthrin is a potent and orally active cellular Leukotriene (LT) biosynthesis inhibitor. Tryptanthrin has anticancer activity. Tryptanthrin suppresses the expression levels of NOS1, COX-2, and NF-κB and regulates the expression levels of IL-2, IL-10, and TNF-α .

Indirubin (Standard) Couroupitine B (Standard); indigo red (Standard); indigopurpurin (Standard)	Alkaloids Structural Classification other families Plants Indole Alkaloids Source Classification	Reference Standards Apoptosis
Indirubin (Standard) is the analytical standard of Indirubin. This product is intended for research and analytical applications. Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .

Cephalandole B	Alkaloids Acanthaceae Plants Indole Alkaloids Jacobaea cannabifolia (Less.) E. Wiebe Source Classification	Others
Cephalandole B is an indigo alkaloid that has the activity of inhibiting IL-17A gene expression. Cephalandole B significantly inhibited the activity of IL-17A luciferase reporter gene in Jukat cells, and this inhibitory effect was dose-dependent. Cephalandole B may have important application prospects in inflammation-related research .

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indigo

Inhibitors & Agonists

Fluorescent Dyes

NaturalProducts

Natural
Products