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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
intraperitoneal toxicity
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "intraperitoneal toxicity" in MCE Product Catalog:
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Research Areas:
MS6105 is a PROTAC degrader targeting LDHA and LDHB, with DC50 values of 38 nM and 74 nM for degrading LDHA and LDHB in PANC-1 cells, respectively, and no hook effect is observed at high concentrations. MS6105 inhibits the proliferation of pancreatic cancer cells, and no obvious toxicity is observed after intraperitoneal administration in mice. MS6105 can be used for pancreatic cancer-related research .
Cat. No.: HY-N4031
CAS No.: 82375-29-9
MU1210 (compound 12f), a chemical probe, is an inhibitor of CDC-like kinases Clk1, Clk2, and Clk4 (with IC50 values of 8, 20, and 12 nM respectively), with IC50 for HIPK1 and DYRK2 are 187 and 1309 nM. MU1210 also has favorable pharmacokinetic characteristics (in mice, 10 mg/kg, intraperitoneal injection: Cmax=1.24 μM, T1/2=58 minutes; no acute toxicity observed) .
Cat. No.: HY-W012663
CAS No.: 106-69-4
Research Areas:
1,2,6-Hexanetriol, a polyol, is an intermediate for wetting agents, solvents, and pharmaceuticals with excellent moisturizing property. 1,2,6-Hexanetriol is a humectant and plasticizer for hydrophilic films. 1,2,6-Hexanetriol has no significant toxicity in rats, rabbits, and dogs via oral (16 mL/kg), intraperitoneal (10 g/kg) and intravenous (5.6 mL/kg) routes. 1,2,6-Hexanetriol can be used for the cosmetics and resin industries .
Cat. No.: HY-N11732
CAS No.: 36375-21-0
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Cat. No.: HY-167108
CAS No.: 91635-05-1
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3-Glyoxyloylcoumarin is a Coumarin (HY-N0709) derivative with moderate to low acute toxicity. 3-Glyoxyloylcoumarin is applicable to studies on urinary system toxicity .
Cat. No.: HY-N18254
CAS No.: 86500-43-8
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Cat. No.: HY-N21836
CAS No.: 76551-64-9
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Cat. No.: HY-W072994
CAS No.: 1338-02-9
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Research Areas:
Copper naphthenate is an organocopper compound with the properties of a fungicide, preservative, oil-borne protectant, and toxicant. Copper naphthenate increases serum and urine copper levels in exposed populations, causes skin irritation, and induces intraperitoneal toxicity in rats. Copper naphthenate inhibits the growth of decay fungi and molds on moso bamboo, kills the free-living stages of Ichthyophthirius multifiliis, and controls wood-boring insects and termites .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
