O-Demethylrotenone
O-Demethylrotenone is a rotenone (HY-B1756) derivative and a photodegradation product of rotenone that induces acute intraperitoneal toxicity. The acute intraperitoneal LD50 of O-Demethylrotenone in Mus musculus is 8.0 mg/kg.
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- CAS No.: 36375-21-0
- Formule: C22H20O6
- Masse moléculaire:380.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
O-Demethylrotenone (1 g rotenone, equimolar boron tribromide, 12 mL dichloromethane; 2 min at -10 °C) is synthesized from rotenone via demethylation with boron tribromide, exhibits characteristic spectral and physical properties, and can be converted back to rotenone via methylation[1].
O-Demethylrotenone (1 g rotenone in 600 mL methanol; 2 hr ultraviolet irradiation with oxygen bubbling) is a neutral product of rotenone photodecomposition in oxygenated methanol solution under ultraviolet irradiation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:white mice (adult male)[1]
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Dosage:8.0 mg/kg
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Administration:i.p.; single dose
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Result:Determined a 24-hour intraperitoneal LD50 of 8.0 mg/kg.
Chemical Information
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CAS No. 36375-21-0
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Masse moléculaire 380.39
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Formule C22H20O6
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SMILES
O=C1[C@@]2([H])C3=CC(OC)=C(O)C=C3OC[C@@]2([H])OC4=C(C[C@@H](O5)C(C)=C)C5=CC=C41
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
O-Demethylrotenone Related Classifications
HY-N11732 Related Classifications
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