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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
278 Results for "
libraries
" in MedChemExpress (MCE) Product Catalog:
Products (278)
278 Results for "libraries" in MCE Product Catalog:
1
1 Cited Publications
製品番号: HY-W002805
CAS 番号: 66572-56-3
製品番号: HY-175452
Target:
研究分野:
MRT-3486 is a molecular glue degrader.MRT-3486 induces ternary complex formation between CRBN and predicted β-hairpin G-loop proteins.MRT-3486 is selected from an internal compound library for proximity-ligation experiments .
製品番号: HY-76562
CAS 番号: 26218-75-7
別名: ABAO
Target:
研究分野:
2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n
製品番号: HY-P5082
CAS 番号: 2243207-00-1
Target:
研究分野:
製品番号: HY-42045
CAS 番号: 321724-19-0
Target:
研究分野:
CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation .
製品番号: HY-152197
CAS 番号: 938893-79-9
Tankyrase-IN-3 is a tankyrase 1 (TNKS1) inhibitor with an IC50 value of 22 nM. Tankyrase-IN-3 can be used for the research of cancer .
製品番号: HY-W457949
CAS 番号: 2758431-96-6
研究分野:
Pomalidomide 4'-alkylC4-azide (Compound 2) is an azide compound containing a MIDI group and is one of the compounds used to construct a library of MIDI azide compounds. Pomalidomide 4'-alkylC4-azide is an E3 ligase ligand and linker conjugate (E3 Ligase Ligand-Linker Conjugate). Pomalidomide 4'-alkylC4-azide can be used to develop research on PROTAC degraders .
製品番号: HY-120333
CAS 番号: 147317-15-5
Category:
Infection Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Disease Research Disease Research Fields Other Antibiotics
Target:
製品番号: HY-178755
Target:
研究分野:
DEL1187-126-5-80 is a JAK3 inhibitor with IC50s of 52 and 7.9 nM against JAK3 WT in 0 and 60 min. DEL1187-126-5-80 has no activity at all towards the C909S mutant, JAK1, JAK2, and TYK2. DEL1187-126-5-80 can be used for the study of immune-mediated diseases .
製品番号: HY-178763
Target:
研究分野:
DEL1187-126-28-16 is a JAK3 inhibitor with IC50s of 10 and 0.97 nM against JAK3 WT in 0 and 60 min. DEL1187-126-28-16 has no activity at all towards the C909S mutant, JAK1, JAK2, and TYK2. DEL1187-126-28-16 can be used for the study of immune-mediated diseases .
SQ609 is a lead compound from a library of dipiperidines. SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells. SQ609 displays a potent antitubercular activity .
製品番号: HY-178714
Target:
研究分野:
JNJ627 is a small molecule allosteric inhibitor of IL-17A with a KD of 92 nM. JNJ627 effectively inhibits the binding of IL-17A and IL-17RA, with an IC50 value of 16 nM. JNJ627 is capable of inhibiting the secretion of G-CSF (granulocyte colony-stimulating factor) caused by IL-17A stimulation. JNJ627 can be used for the study of autoimmune diseases (such as psoriasis) .
製品番号: HY-159587
Target:
研究分野:
P300-IN-4 (compound 6) is a (p300) inhibitor with the IC50 of 12.2 μM.
製品番号: HY-116557
CAS 番号: 140652-99-9
Target:
研究分野:
JCP-265 is a compound used for in vivo phenotypic screening of small molecule libraries, which has the activity of screening molecules that regulate cell function. JCP-265 uses molecular cell barcoding technology to directly screen small molecule libraries in vivo for studying complex physiological processes, such as screening compounds related to targets in pancreatic cancer metastasis seeding studies.
製品番号: HY-123759
CAS 番号: 1883803-09-5
Target:
研究分野:
sEH-IN-12 is a potent soluble epoxide hydrolase (sEH) inhibitor with the property of inhibiting sEH activity. sEH-IN-12 was successfully used in the construction and selection of small molecule libraries, showing excellent biological activity. The development of sEH-IN-12 provides a new tool for drug discovery targeting sEH .
製品番号: HY-D3193
CAS 番号: 1361203-33-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
