DEL1187-126-28-16
DEL1187-126-28-16 is a JAK3 inhibitor with IC50s of 10 and 0.97 nM against JAK3 WT in 0 and 60 min. DEL1187-126-28-16 has no activity at all towards the C909S mutant, JAK1, JAK2, and TYK2. DEL1187-126-28-16 can be used for the study of immune-mediated diseases.
For research use only. We do not sell to patients.
- Formula: C22H24ClN7O2
- Molecular Weight:453.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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JAK3 0.97 nM (IC50) |
Chemical Information
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Molecular Weight 453.92
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Formula C22H24ClN7O2
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SMILES
CNC(CC1=CC=C(C=C1)NC2=NC=NC(NCC3=CC=CC(CNC(CCl)=O)=C3)=N2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)