Search Result
Results for "
liquid chromatography
" in MedChemExpress (MCE) Product Catalog:
2
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-117695
-
|
6-Aminoquinolyl-N-hydroxysccinimidyl carbamate
|
Fluorescent Dye
|
Others
|
|
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
|
-
-
- HY-W027544
-
|
7-Methoxycoumarin-4-acetic acid
|
Fluorescent Dye
|
Others
|
|
MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .
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- HY-N3286
-
|
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Influenza Virus
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Others
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Methyl 4-O-feruloylquinate (4-O-Feruloylquinic acid methyl ester) is a natural product. Methyl 4-O-feruloylquinate can be purified from Stemona Japonica by preparative high-performance liquid chromatography. Methyl 4-O-feruloylquinate has anti-H5N1 activity with a 3% protective rate at 5 μM in MDCK cells .
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- HY-I0169
-
|
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Drug Metabolite
|
Neurological Disease
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(R)-Amino-N-benzyl-3-methoxypropionamide is a key intermediate for the synthesis of the antiepileptic agent (R)-Lacosamide. To improve its chiral purity and chemical stability, (R)-Amino-N-benzyl-3-methoxypropionamide can react with phosphoric acid to form a phosphate salt. Detected by high performance liquid chromatography (HPLC), this phosphate salt exhibits extremely high chiral purity, with the content of the R-enantiomer reaching up to 99.37% .
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-
-
- HY-D2171
-
|
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Fluorescent Dye
|
Others
|
|
AF488 DBCO is a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO mediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .
|
-
-
- HY-DY1070
-
|
|
Fluorescent Dye
|
Others
|
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) (solution) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels . Solvent and concentration: DMSO: 10 mM The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
-
- HY-P3570
-
|
Lom-AKH-II
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .
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-
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- HY-W100959
-
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Tetramethylquinone
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Drug Derivative
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Others
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Duroquinone (Tetramethylquinone) is a model compound of amphiphilic quinone, which can be used as an oxidative-reductive activity probe. Duroquinone can be easily reduced by biological systems to hydrogen peroxide (DQH₂) or semi-quinone free radicals (DQ•⁻). Duroquinone can freely pass through the cell membrane, facilitating the study of the electron transfer process inside and outside the cells. Duroquinone can be used to investigate the relationship between metabolism in the pulmonary circulation and endothelial cells .
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- HY-116245
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|
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Biochemical Assay Reagents
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Others
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Octanophenone is a substance used as a test compound in liquid chromatography research to study related properties such as particle diffusion within the column. A series of experiments showed that the Titan-C18 column in which it is located has some special property differences compared to other columns.
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- HY-P3572
-
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Lom-AKH-I
|
Endogenous Metabolite
|
Endocrinology
|
|
Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .
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- HY-123819
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|
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CXCR
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Infection
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KRH-1636 is a CXC chemokine receptor (CXCR) 4 antagonist. KRH-1636 can be used in HIV-1 research .
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- HY-W097777
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4,4'-Dimethoxybenzoin; 4,4′-DMB
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Fluorescent Dye
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Others
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Anisoin (4,4'-Dimethoxybenzoin) is a pre-chromatographic fluorogenic labelling reagent for (liquid chromatography) analysis of guanidino compounds (Ex/Em = 325/435 nm) .
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- HY-W009545
-
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1-Decanesulfonic acid sodium
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Biochemical Assay Reagents
|
Others
|
|
Sodium decane-1-sulfonate is an anionic surfactant used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography.
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-
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- HY-115689
-
|
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Others
|
Others
|
|
Maohuoside B is a flavonoid, that can be isolated from Epimedium koreanum Nakai .
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- HY-158725
-
|
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Endogenous Metabolite
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Others
|
|
N-Octadecenoyl-(cis-9) -Sulfatide is a glycolipid found in the brains of mice. N-Octadecenoyl-(cis-9) -Sulfatide can be used as a standard for the determination of C18:13 '-mergogalactosyllactose in dry blood stains of patients with chromatic leukodystrophy (MLD) by ultra-high performance liquid chromatography-mass spectrometry (UPLC-MS) .
|
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- HY-N17239
-
|
|
TNF Receptor
Interleukin Related
NO Synthase
|
Inflammation/Immunology
|
|
Oleracone is a type of alkaloid that can be found in Portulaca oleracea L.. Oleracone exhibits a significant anti-inflammatory effect in the RAW 264.7 macrophage model induced by LPS (HY-D1056), capable of inhibiting NO production and significantly suppressing the secretion of pro-inflammatory cytokines TNF-α, IL-6, and prostaglandin E₂ (PGE₂). Oleracone can be used for the study of inflammatory diseases .
|
-
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- HY-35556
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-
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- HY-W009545R
-
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1-Decanesulfonic acid sodium (Standard)
|
Reference Standards
Biochemical Assay Reagents
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Others
|
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Sodium decane-1-sulfonate (Standard) is the analytical standard of Sodium decane-1-sulfonate. This product is intended for research and analytical applications. Sodium decane-1-sulfonate is an anionic surfactant used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography.
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- HY-16675
-
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Docetaxel Impurity 2
|
Microtubule/Tubulin
|
Cancer
|
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7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is a impurity of docetaxel detected by high performance liquid chromatography (HPLC).
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- HY-165127
-
|
(+)-Octopinic acid
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Others
|
Others
|
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Octopinic acid ((+)-Octopinic acid) is a biomarker (opine) for plant crown gall or hairy root disease detected by ultra-performance liquid chromatography-electrospray ionization quadrupole time-of-flight mass spectrometry with activity useful for disease diagnosis and analysis.
|
-
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- HY-165109
-
|
1,3-Olein-2-laurin; TG(18:1/12:0/18:1)
|
Endogenous Metabolite
|
Others
|
|
1,3-Dioleoyl-2-lauroyl glycerol (1,3-Olein-2-laurin), a compound in the triglyceride composition of human milk, was identified and quantified by liquid chromatography-mass spectrometry, and a targeted analytical approach was developed.
|
-
-
- HY-131589
-
|
Atenolol acid
|
Endogenous Metabolite
|
Others
|
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Metoprolol acid (Atenolol acid) is a urinary metabolite with no pharmacological activity. Metoprolol acid does not exert its pharmacological effects in vivo. Metoprolol acid can be detected by solid phase extraction and reversed phase high performance liquid chromatography. The analysis of metoprolol acid requires specific conditions, such as the use of fluorescence detection and specific eluents .
|
-
-
- HY-165095
-
|
1,2-Palmitolein-3-palmitin; TG(16:1/16:1/16:0)
|
Others
|
Others
|
|
1,2-Dipalmitoleoyl-3-palmitoyl-rac-glycerol (1,2-Palmitolein-3-palmitin) is a triglyceride used for serum lipidomics analysis by liquid chromatography-mass spectrometry. This method can effectively separate and detect lipids in positive and negative ionization modes and has certain performance in the identification and characterization of serum triglycerides.
|
-
-
- HY-N12143
-
|
|
Others
|
Others
|
|
Acetylthevetin A is a natural product isolated from oleander (Cascabela thevetioides) .
|
-
-
- HY-131589R
-
|
Atenolol acid (Standard)
|
Endogenous Metabolite
Reference Standards
|
Others
|
|
Metoprolol acid (Standard) is the analytical standard of Metoprolol acid. This product is intended for research and analytical applications. Metoprolol acid (Atenolol acid) is a urinary metabolite with no pharmacological activity. Metoprolol acid does not exert its pharmacological effects in vivo. Metoprolol acid can be detected by solid phase extraction and reversed phase high performance liquid chromatography. The analysis of metoprolol acid requires specific conditions, such as the use of fluorescence detection and specific eluents .
|
-
-
- HY-W040821R
-
|
|
Reference Standards
Endogenous Metabolite
|
Neurological Disease
|
|
Metoprolol acid (Standard) is the analytical standard of Metoprolol acid. This product is intended for research and analytical applications. Metoprolol acid (Atenolol acid) is a urinary metabolite with no pharmacological activity. Metoprolol acid does not exert its pharmacological effects in vivo. Metoprolol acid can be detected by solid phase extraction and reversed phase high performance liquid chromatography. The analysis of metoprolol acid requires specific conditions, such as the use of fluorescence detection and specific eluents .
|
-
-
- HY-116870
-
|
|
Parasite
|
Infection
|
|
Vamidothion is a polar organophosphorus insecticide and acaricide with biological activity against insects and mites. Vamidothion is degraded by human serum albumin (HSA) and promotes adduct formation with tyrosine residues. The phosphate amino acid adducts formed after the reaction of vamidothion with HSA are detected by liquid chromatography quadrupole-Orbitrap mass spectrometry. The metabolites of vamidothion can be used in forensic toxicology to help determine deaths caused by organophosphorus poisoning .
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-
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- HY-W027544S
-
|
7-Methoxycoumarin-4-acetic acid-d3
|
Isotope-Labeled Compounds
Fluorescent Dye
|
Others
|
|
MCA-d3 (7-Methoxycoumarin-4-acetic acid3) is the deuterium labeled MCA (HY-W027544) . MCA is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .
|
-
-
- HY-120512
-
|
|
Fluorescent Dye
|
Others
|
|
5-Phenyl-4E-pentenol is a product of the peroxidase-catalyzed reduction of PPHP. 5-Phenyl-4E-pentenol can be rapidly isolated by solid phase extraction and quantified by isocratic reversed-phase high performance liquid chromatography (HPLC) with UV detection. 5-Phenyl-4E-pentenol is a fluorescent dye that can be used to determine the kinetic properties of heme-containing and non-heme peroxidases and to evaluate the ability of oxidative compounds to serve as substrates for peroxidase reduction. .
|
-
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- HY-N9808
-
|
|
Others
|
Others
|
|
Creoside III is a glycoside compound, mainly used as a component of natural product libraries for potential activity screening studies in the field of natural product chemistry. Creoside III can be naturally extracted from the dried roots of Rhodiola crenulata (a plant of the genus Rhodiola in the Crassulaceae family) through methanol reflux extraction, column chromatography separation, and high-performance liquid chromatography purification .
|
-
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- HY-177192
-
|
DMPS
|
Biochemical Assay Reagents
|
Others
|
|
1,2-Dimyristoyl-sn-glycero-3-phosphoserine (DMPS) is an anionic, negatively charged phosphatidylserine phospholipid. 1,2-Dimyristoyl-sn-glycero-3-phosphoserine acts as an internal standard for liquid chromatography/mass spectrometry analyses .
|
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- HY-127151
-
|
Levophencynonate hydrochloride
|
Endogenous Metabolite
|
Neurological Disease
|
|
Levophencynonate is a muscarinic receptor antagonist with anticholinergic activity. The biological activity of levophencynonate makes it a key target for the determination of its concentration in human plasma in medical research. Levophencynonate was analyzed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) and showed good specificity and linearity .
|
-
-
- HY-135543
-
|
|
Endogenous Metabolite
|
Neurological Disease
|
|
Levophencynonate is a muscarinic receptor antagonist with anticholinergic activity. The biological activity of levophencynonate makes it a key target for the determination of its concentration in human plasma in medical research. Levophencynonate was analyzed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) and showed good specificity and linearity .
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-
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- HY-N17719
-
|
|
Others
|
Others
|
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(2S)-Eriodictyol-5-O-β-D-glucopyranoside (Compound 1b) is a type of flavanone glucoside compound, which can be found in Balanophora involucrate Hook. f .
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- HY-N13081
-
|
|
Others
|
Cancer
|
|
3-Oxo-cinobufagin (compound 8) is a potential anticancer compound that can be isolated from the broth of M. spinosus by high-performance liquid chromatography. Compared to other isolated compounds, the hydroxyl group at the C-5 position of 3-Oxo-cinobufagin is further oxidized or isomerized, significantly reducing its cytotoxic activity against most cell lines (except HEL), while increasing its activity against the BEL cell line. The IC50 values of 3-Oxo-cinobufagin's cytotoxicity against cancer cells are: 71.3 μM (HepG2), 90.2 μM (SMMC-7221), 0.11 μM (BEL-7402), 72.5 μM (K562), 5.3 μM (HL-60), and 12 nM (HEL) .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-117695
-
|
6-Aminoquinolyl-N-hydroxysccinimidyl carbamate
|
Fluorescent Dyes
|
|
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
|
-
- HY-W027544
-
|
7-Methoxycoumarin-4-acetic acid
|
Fluorescent Dyes
|
|
MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .
|
-
- HY-D2171
-
|
|
Fluorescent Dyes
|
|
AF488 DBCO is a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO mediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .
|
-
- HY-DY1070
-
|
|
Fluorescent Dyes
|
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) (solution) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels . Solvent and concentration: DMSO: 10 mM The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-120512
-
|
|
Fluorescent Dyes
|
|
5-Phenyl-4E-pentenol is a product of the peroxidase-catalyzed reduction of PPHP. 5-Phenyl-4E-pentenol can be rapidly isolated by solid phase extraction and quantified by isocratic reversed-phase high performance liquid chromatography (HPLC) with UV detection. 5-Phenyl-4E-pentenol is a fluorescent dye that can be used to determine the kinetic properties of heme-containing and non-heme peroxidases and to evaluate the ability of oxidative compounds to serve as substrates for peroxidase reduction. .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W009545
-
|
1-Decanesulfonic acid sodium
|
Biochemical Assay Reagents
|
|
Sodium decane-1-sulfonate is an anionic surfactant used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography.
|
-
- HY-W009545R
-
|
1-Decanesulfonic acid sodium (Standard)
|
Biochemical Assay Reagents
|
|
Sodium decane-1-sulfonate (Standard) is the analytical standard of Sodium decane-1-sulfonate. This product is intended for research and analytical applications. Sodium decane-1-sulfonate is an anionic surfactant used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P5531
-
|
|
Peptides
|
Others
|
|
beta-Casein phosphopeptide is a biological active peptide. (Bovine -Casein, monophosphopeptide (phospho-Serine) can be used for characterization of affinity purified phosphorylated peptides in liquid chromatography and for the analysis or detection of phosphorylated peptides in mass spectrometry.)
|
-
- HY-P3570
-
|
Lom-AKH-II
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .
|
-
- HY-P3572
-
|
Lom-AKH-I
|
Endogenous Metabolite
|
Endocrinology
|
|
Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N3286
-
-
-
- HY-115689
-
-
-
- HY-N17239
-
-
-
- HY-N12143
-
-
-
- HY-W040821R
-
-
-
- HY-N9808
-
|
|
Structural Classification
Monophenols
Rhodiola rosea Linn.
Crassulaceae
Phenols
Plants
Source Classification
|
Others
|
|
Creoside III is a glycoside compound, mainly used as a component of natural product libraries for potential activity screening studies in the field of natural product chemistry. Creoside III can be naturally extracted from the dried roots of Rhodiola crenulata (a plant of the genus Rhodiola in the Crassulaceae family) through methanol reflux extraction, column chromatography separation, and high-performance liquid chromatography purification .
|
-
-
- HY-N17719
-
-
-
- HY-N13081
-
|
|
Microorganisms
Steroids
Source Classification
|
Others
|
|
3-Oxo-cinobufagin (compound 8) is a potential anticancer compound that can be isolated from the broth of M. spinosus by high-performance liquid chromatography. Compared to other isolated compounds, the hydroxyl group at the C-5 position of 3-Oxo-cinobufagin is further oxidized or isomerized, significantly reducing its cytotoxic activity against most cell lines (except HEL), while increasing its activity against the BEL cell line. The IC50 values of 3-Oxo-cinobufagin's cytotoxicity against cancer cells are: 71.3 μM (HepG2), 90.2 μM (SMMC-7221), 0.11 μM (BEL-7402), 72.5 μM (K562), 5.3 μM (HL-60), and 12 nM (HEL) .
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W027544S
-
|
|
|
MCA-d3 (7-Methoxycoumarin-4-acetic acid3) is the deuterium labeled MCA (HY-W027544) . MCA is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-D2171
-
|
|
|
DBCO
|
|
AF488 DBCO is a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO mediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .
|
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