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liquid chromatography

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35

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5

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2

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Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117695
    AQC
    5+ Cited Publications

    6-Aminoquinolyl-N-hydroxysccinimidyl carbamate

    Fluorescent Dye Others
    AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
    AQC
  • HY-W027544

    7-Methoxycoumarin-4-acetic acid

    Fluorescent Dye Others
    MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .
    MCA
  • HY-N3286

    Influenza Virus Others
    Methyl 4-O-feruloylquinate (4-O-Feruloylquinic acid methyl ester) is a natural product. Methyl 4-O-feruloylquinate can be purified from Stemona Japonica by preparative high-performance liquid chromatography. Methyl 4-O-feruloylquinate has anti-H5N1 activity with a 3% protective rate at 5 μM in MDCK cells .
    Methyl 4-O-feruloylquinate
  • HY-I0169

    Drug Metabolite Neurological Disease
    (R)-Amino-N-benzyl-3-methoxypropionamide is a key intermediate for the synthesis of the antiepileptic agent (R)-Lacosamide. To improve its chiral purity and chemical stability, (R)-Amino-N-benzyl-3-methoxypropionamide can react with phosphoric acid to form a phosphate salt. Detected by high performance liquid chromatography (HPLC), this phosphate salt exhibits extremely high chiral purity, with the content of the R-enantiomer reaching up to 99.37% .
    (R)-Amino-N-benzyl-3-methoxypropionamide
  • HY-D2171

    Fluorescent Dye Others
    AF488 DBCO is a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO mediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .
    AF488 DBCO
  • HY-DY1070

    Fluorescent Dye Others
    AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) (solution) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
    Solvent and concentration: DMSO: 10 mM
    The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
    AQC (solution)
  • HY-P3570

    Lom-AKH-II

    Endogenous Metabolite Metabolic Disease
    Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .
    Adipokinetic hormone II (Locusta migratoria)
  • HY-W100959

    Tetramethylquinone

    Drug Derivative Others
    Duroquinone (Tetramethylquinone) is a model compound of amphiphilic quinone, which can be used as an oxidative-reductive activity probe. Duroquinone can be easily reduced by biological systems to hydrogen peroxide (DQH₂) or semi-quinone free radicals (DQ•⁻). Duroquinone can freely pass through the cell membrane, facilitating the study of the electron transfer process inside and outside the cells. Duroquinone can be used to investigate the relationship between metabolism in the pulmonary circulation and endothelial cells .
    Duroquinone
  • HY-116245

    Biochemical Assay Reagents Others
    Octanophenone is a substance used as a test compound in liquid chromatography research to study related properties such as particle diffusion within the column. A series of experiments showed that the Titan-C18 column in which it is located has some special property differences compared to other columns.
    Octanophenone
  • HY-P3572

    Lom-AKH-I

    Endogenous Metabolite Endocrinology
    Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .
    Adipokinetic hormone I (Locusta migratoria)
  • HY-123819

    CXCR Infection
    KRH-1636 is a CXC chemokine receptor (CXCR) 4 antagonist. KRH-1636 can be used in HIV-1 research .
    KRH-1636
  • HY-W097777

    4,4'-Dimethoxybenzoin; 4,4′-DMB

    Fluorescent Dye Others
    Anisoin (4,4'-Dimethoxybenzoin) is a pre-chromatographic fluorogenic labelling reagent for (liquid chromatography) analysis of guanidino compounds (Ex/Em = 325/435 nm) .
    Anisoin
  • HY-W009545

    1-Decanesulfonic acid sodium

    Biochemical Assay Reagents Others
    Sodium decane-1-sulfonate is an anionic surfactant used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography.
    Sodium decane-1-sulfonate
  • HY-115689

    Others Others
    Maohuoside B is a flavonoid, that can be isolated from Epimedium koreanum Nakai .
    Maohuoside B
  • HY-158725

    Endogenous Metabolite Others
    N-Octadecenoyl-(cis-9) -Sulfatide is a glycolipid found in the brains of mice. N-Octadecenoyl-(cis-9) -Sulfatide can be used as a standard for the determination of C18:13 '-mergogalactosyllactose in dry blood stains of patients with chromatic leukodystrophy (MLD) by ultra-high performance liquid chromatography-mass spectrometry (UPLC-MS) .
    N-Octadecenoyl-(cis-9)-sulfatide
  • HY-N17239

    TNF Receptor Interleukin Related NO Synthase Inflammation/Immunology
    Oleracone is a type of alkaloid that can be found in Portulaca oleracea L.. Oleracone exhibits a significant anti-inflammatory effect in the RAW 264.7 macrophage model induced by LPS (HY-D1056), capable of inhibiting NO production and significantly suppressing the secretion of pro-inflammatory cytokines TNF-α, IL-6, and prostaglandin E₂ (PGE₂). Oleracone can be used for the study of inflammatory diseases .
    Oleracone
  • HY-35556

    Fluorescent Dye Cardiovascular Disease Metabolic Disease
    9-Aminophenanthrene is a type of polycyclic aromatic amine compound, which can be used as a fluorescent labeling reagent for free fatty acids (FFA) .
    9-Aminophenanthrene
  • HY-W009545R

    1-Decanesulfonic acid sodium (Standard)

    Reference Standards Biochemical Assay Reagents Others
    Sodium decane-1-sulfonate (Standard) is the analytical standard of Sodium decane-1-sulfonate. This product is intended for research and analytical applications. Sodium decane-1-sulfonate is an anionic surfactant used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography.
    Sodium decane-1-sulfonate (Standard)
  • HY-16675

    Docetaxel Impurity 2

    Microtubule/Tubulin Cancer
    7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is a impurity of docetaxel detected by high performance liquid chromatography (HPLC).
    7-Epi-10-oxo-docetaxel
  • HY-165127

    (+)-Octopinic acid

    Others Others
    Octopinic acid ((+)-Octopinic acid) is a biomarker (opine) for plant crown gall or hairy root disease detected by ultra-performance liquid chromatography-electrospray ionization quadrupole time-of-flight mass spectrometry with activity useful for disease diagnosis and analysis.
    Octopinic acid
  • HY-165109

    1,3-Olein-2-laurin; TG(18:1/12:0/18:1)

    Endogenous Metabolite Others
    1,3-Dioleoyl-2-lauroyl glycerol (1,3-Olein-2-laurin), a compound in the triglyceride composition of human milk, was identified and quantified by liquid chromatography-mass spectrometry, and a targeted analytical approach was developed.
    1,3-Dioleoyl-2-lauroyl glycerol
  • HY-131589

    Atenolol acid

    Endogenous Metabolite Others
    Metoprolol acid (Atenolol acid) is a urinary metabolite with no pharmacological activity. Metoprolol acid does not exert its pharmacological effects in vivo. Metoprolol acid can be detected by solid phase extraction and reversed phase high performance liquid chromatography. The analysis of metoprolol acid requires specific conditions, such as the use of fluorescence detection and specific eluents .
    Metoprolol acid
  • HY-165095

    1,2-Palmitolein-3-palmitin; TG(16:1/16:1/16:0)

    Others Others
    1,2-Dipalmitoleoyl-3-palmitoyl-rac-glycerol (1,2-Palmitolein-3-palmitin) is a triglyceride used for serum lipidomics analysis by liquid chromatography-mass spectrometry. This method can effectively separate and detect lipids in positive and negative ionization modes and has certain performance in the identification and characterization of serum triglycerides.
    1,2-Dipalmitoleoyl-3-palmitoyl-rac-glycerol
  • HY-N12143

    Others Others
    Acetylthevetin A is a natural product isolated from oleander (Cascabela thevetioides) .
    Acetylthevetin A
  • HY-131589R

    Atenolol acid (Standard)

    Endogenous Metabolite Reference Standards Others
    Metoprolol acid (Standard) is the analytical standard of Metoprolol acid. This product is intended for research and analytical applications. Metoprolol acid (Atenolol acid) is a urinary metabolite with no pharmacological activity. Metoprolol acid does not exert its pharmacological effects in vivo. Metoprolol acid can be detected by solid phase extraction and reversed phase high performance liquid chromatography. The analysis of metoprolol acid requires specific conditions, such as the use of fluorescence detection and specific eluents .
    Metoprolol acid (Standard)
  • HY-W040821R

    Reference Standards Endogenous Metabolite Neurological Disease
    Metoprolol acid (Standard) is the analytical standard of Metoprolol acid. This product is intended for research and analytical applications. Metoprolol acid (Atenolol acid) is a urinary metabolite with no pharmacological activity. Metoprolol acid does not exert its pharmacological effects in vivo. Metoprolol acid can be detected by solid phase extraction and reversed phase high performance liquid chromatography. The analysis of metoprolol acid requires specific conditions, such as the use of fluorescence detection and specific eluents .
    DL-Homocysteine (Standard)
  • HY-116870

    Parasite Infection
    Vamidothion is a polar organophosphorus insecticide and acaricide with biological activity against insects and mites. Vamidothion is degraded by human serum albumin (HSA) and promotes adduct formation with tyrosine residues. The phosphate amino acid adducts formed after the reaction of vamidothion with HSA are detected by liquid chromatography quadrupole-Orbitrap mass spectrometry. The metabolites of vamidothion can be used in forensic toxicology to help determine deaths caused by organophosphorus poisoning .
    Vamidothion
  • HY-W027544S

    7-Methoxycoumarin-4-acetic acid-d3

    Isotope-Labeled Compounds Fluorescent Dye Others
    MCA-d3 (7-Methoxycoumarin-4-acetic acid3) is the deuterium labeled MCA (HY-W027544) . MCA is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .
    MCA-d3
  • HY-120512

    Fluorescent Dye Others
    5-Phenyl-4E-pentenol is a product of the peroxidase-catalyzed reduction of PPHP. 5-Phenyl-4E-pentenol can be rapidly isolated by solid phase extraction and quantified by isocratic reversed-phase high performance liquid chromatography (HPLC) with UV detection. 5-Phenyl-4E-pentenol is a fluorescent dye that can be used to determine the kinetic properties of heme-containing and non-heme peroxidases and to evaluate the ability of oxidative compounds to serve as substrates for peroxidase reduction. .
    5-Phenyl-4E-pentenol
  • HY-N9808

    Others Others
    Creoside III is a glycoside compound, mainly used as a component of natural product libraries for potential activity screening studies in the field of natural product chemistry. Creoside III can be naturally extracted from the dried roots of Rhodiola crenulata (a plant of the genus Rhodiola in the Crassulaceae family) through methanol reflux extraction, column chromatography separation, and high-performance liquid chromatography purification .
    Creoside III
  • HY-177192

    DMPS

    Biochemical Assay Reagents Others
    1,2-Dimyristoyl-sn-glycero-3-phosphoserine (DMPS) is an anionic, negatively charged phosphatidylserine phospholipid. 1,2-Dimyristoyl-sn-glycero-3-phosphoserine acts as an internal standard for liquid chromatography/mass spectrometry analyses .
    1,2-Dimyristoyl-sn-glycero-3-phosphoserine
  • HY-127151

    Levophencynonate hydrochloride

    Endogenous Metabolite Neurological Disease
    Levophencynonate is a muscarinic receptor antagonist with anticholinergic activity. The biological activity of levophencynonate makes it a key target for the determination of its concentration in human plasma in medical research. Levophencynonate was analyzed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) and showed good specificity and linearity .
    R-(-)-Phencynonate hydrochloride
  • HY-135543

    Endogenous Metabolite Neurological Disease
    Levophencynonate is a muscarinic receptor antagonist with anticholinergic activity. The biological activity of levophencynonate makes it a key target for the determination of its concentration in human plasma in medical research. Levophencynonate was analyzed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) and showed good specificity and linearity .
    Levophencynonate
  • HY-N17719

    Others Others
    (2S)-Eriodictyol-5-O-β-D-glucopyranoside (Compound 1b) is a type of flavanone glucoside compound, which can be found in Balanophora involucrate Hook. f .
    (2S)-Eriodictyol-5-O-β-D-glucopyranoside
  • HY-N13081

    Others Cancer
    3-Oxo-cinobufagin (compound 8) is a potential anticancer compound that can be isolated from the broth of M. spinosus by high-performance liquid chromatography. Compared to other isolated compounds, the hydroxyl group at the C-5 position of 3-Oxo-cinobufagin is further oxidized or isomerized, significantly reducing its cytotoxic activity against most cell lines (except HEL), while increasing its activity against the BEL cell line. The IC50 values of 3-Oxo-cinobufagin's cytotoxicity against cancer cells are: 71.3 μM (HepG2), 90.2 μM (SMMC-7221), 0.11 μM (BEL-7402), 72.5 μM (K562), 5.3 μM (HL-60), and 12 nM (HEL) .
    3-Oxo-cinobufagin

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