62935-72-2
62935-72-2
Chemical Structure
MCA
Synonym(s): 7-Methoxycoumarin-4-acetic acid
- CAS. Nr.: 62935-72-2
- Formula:C12H10O5
- Molecular Weight:234.21
IUPAC Name: 2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetic acid
InChIKey: ZEKAXIFHLIITGV-UHFFFAOYSA-N
SMILES: O=C1OC(C=C(OC)C=C2)=C2C(CC(O)=O)=C1
Biological Activity: MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[1][2].
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MCA | 98.87% | MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities. | ||||||||||||||||||||
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References
- [1]. Perera NC, et, al. NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity. J Immunol. 2013 Sep 1;191(5):2700-7. [Content Brief]
- [2]. Choi YH,et, al. Effect of functional groups on the solubilities of coumarin derivatives in supercritical carbon dioxide. Chromatographia. 1998 Jan;47(93-7).
Keywords
