62935-72-2
62935-72-2
Chemical Structure
MCA
Synonym(s): 7-Methoxycoumarin-4-acetic acid
- CAS No.: 62935-72-2
- Formula:C12H10O5
- Molecular Weight:234.21
IUPAC Name: 2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetic acid
InChIKey: ZEKAXIFHLIITGV-UHFFFAOYSA-N
SMILES: O=C1OC(C=C(OC)C=C2)=C2C(CC(O)=O)=C1
Biological Activity: MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MCA | 98.87% | MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities. | ||||||||||||||||||||
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4-Methylumbelliferyl butyrate | 99.01% | 4-Methylumbelliferyl butyrate (4-MUB) is a fluorogenic esterase substrate that is hydrolyzed by esterases to release the fluorescent product 4-methylumbelliferone (HY-N0187). 4-Methylumbelliferyl butyrate is hydrolyzed by the general esterases (GE) of Daphnia magna and Chironomus riparius; it also serves as a substrate for the recombinant mycobacterial carboxylesterase MT2282 (CaeA). 4-Methylumbelliferyl butyrate is used to determine the activity of the S. aureus serine hydrolases FphB and FphH. 4-Methylumbelliferyl butyrate is used in studies related to esterase activity assays. | ||||||||||||||||||||
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7-Acetoxy-4-methylcoumarin | 98.65% | 7-Acetoxy-4-methylcoumarin is an inhibitor of GST.7-Acetoxy-4-methylcoumarin inhibits AFB1-DNA binding in vitro with 36.7% inhibition. | ||||||||||||||||||||
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6,7-Dihydroxy-4-coumarinylacetic acid | 95.58% | 6,7-Dihydroxy-4-coumarinylacetic acid is a potent and selective inhibitor of ALR2. 6,7-Dihydroxy-4-coumarinylacetic acid inhibits ALR2, SDH andALR1 with IC50s of 9.6, 288 and 66.3 μM, respectively. 6,7-Dihydroxy-4-coumarinylacetic acid clearly suppresses galactitol accumulation. | ||||||||||||||||||||
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6,7-Dimethoxy-4-coumarinylacetic acid | 6,7-Dimethoxy-4-coumarinylacetic acid (2-(6,7-Dimethoxy-2-oxo-2H-chromen-4-yl)acetic acid) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. | |||||||||||||||||||||
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7-Hydroxycoumarin-4-acetic acid | 98.71% | 7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm). | ||||||||||||||||||||
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7-Methoxy-4-(trifluoromethyl)coumarin | 98.0% | 7-Methoxy-4-(trifluoromethyl)coumarin (MFC) is a fluorescent substrate for cytochrome P450 and can quantify CYP activity. | ||||||||||||||||||||
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Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate | 97.39% | Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate, a natural coumarins derivative, is exploited for the synthesis of the switchable fluorescent substrates to be used in bacterial enzyme detection. | ||||||||||||||||||||
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7-Dimethylaminocoumarin-4-acetic acid | 98.88% | 7-Dimethylaminocoumarin-4-acetic acid is a fluorescent probe. | ||||||||||||||||||||
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7-(Carboxymethoxy)-4-methylcoumarin | 99.61% | 7-(Carboxymethoxy)-4-methylcoumarin (Compound VIIIa) is the antibacterial and antifungal agent that exhibits inhibitory activity against S. aureus, B. cereus, S. lutea, C. albicans, C. glabrata, and C. parapsilosis. | ||||||||||||||||||||
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7-Acetoxy-4-bromomethylcoumarin | 7-Acetoxy-4-bromomethylcoumarin acts as a fluorescence label for fatty acids. | |||||||||||||||||||||
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References
- [1]. Perera NC, et, al. NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity. J Immunol. 2013 Sep 1;191(5):2700-7. [Content Brief]
- [2]. Choi YH,et, al. Effect of functional groups on the solubilities of coumarin derivatives in supercritical carbon dioxide. Chromatographia. 1998 Jan;47(93-7).
