1 Result for "

mannose-1-phosphate

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "mannose-1-phosphate" in MCE Product Catalog:

GDP-D-mannose disodium
GDP-D-mannose disodium
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Cat. No.: HY-N7389A
CAS No.: 103301-73-1
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Drug Intermediate

GDP-D-mannose disodium consists of GDP-α-D-mannose (HY-N7389B) and GDP-β-D-mannose. GDP-α-D-mannose serves as a donor substrate for mannosyltransferases and acts as a precursor of GDP-β-L-fucose. GDP-α-D-mannose exerts competitive inhibition on GTP (with a Ki value of 14.7 μM) and non-competitive inhibition on mannose-1-P (with a Ki value of 115 μM). GDP-D-mannose disodium is metabolized to GDP-L-fucose (HY-134433) via GMDS (Gmd) and TSTA3 (WcaG) [1] .
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