1 Result for "

murine subcutaneous sponge

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "murine subcutaneous sponge" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-P5353B
Synonyms: IKVAV sequence TFA; Laminin A-chain fragment TFA
Target:  

Peptides

Research Areas:  

Cancer

PA22-2 (IKVAV sequence; Laminin A-chain fragment) TFA is a laminin receptor ligand. PA22-2 TFA competes with laminin for receptor binding sites, thereby mediating biological responses such as cell adhesion, migration, morphology regulation and angiogenesis. PA22-2 TFA promotes adhesion, spreading, directional migration and axon growth of specific cells, and supports endothelial cell mobilization and vascular formation. PA22-2 TFA inhibits laminin-mediated adhesion and migration in melanoma cells, and its antiserum reacts with the laminin A chain and native laminin, effectively blocking cell adhesion and axon growth .
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