172 Results for "

nanocarriers

" in MedChemExpress (MCE) Product Catalog:
Products (172)

172 Results for "nanocarriers" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-128693
CAS No.: 722494-26-0
Purity:  ≥95.0%
Synonyms: Bisperoxovanadium
Target:  

PTEN

Research Areas:  

Neurological Disease Cancer

BpV(HOpic) is a potent and selective inhibitor of PTEN with an IC50 of 14 nM. Nanocarrier-BpV(HOpic) has neuroprotective activity .
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1 Cited Publications
Cat. No.: HY-W127512
CAS No.: 546-18-9
Target:  

Drug Intermediate

Research Areas:  

Others

5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .
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1 Cited Publications
Cat. No.: HY-148775B
Purity:  ≥95.0%
PLGA-PEG-MAL (20KDA-5.0KDA, LA:GA RATIO 40:60) is a biodegradable amphipathic polymeric nanocarrier of poly (lactic-co-glycolic acid)-block-poly (ethylene glycol) (PLGA-PEG-Mal) that allows covalent modification of functional molecules. PLGA-PEG-MAL (20KDA-5.0KDA, LA:GA RATIO 40:60) modified with Angiopep-2 can cross the blood-brain barrier and exhibits targeting selectivity for glioblastoma cells. PLGA-PEG-MAL (20KDA-5.0KDA, LA:GA RATIO 40:60) can capture tumor-derived protein antigens, and exerts immunomodulatory effects when conjugated with anti-OX40 antibody; when used in combination with A2-CL/Dbait nanoparticles and radiotherapy, it prolongs survival time and reduces tumor volume in glioblastoma mouse models. PLGA-PEG-MAL (20KDA-5.0KDA, LA:GA RATIO 40:60) can be used for studies related to bacterial wound infections and glioblastoma .
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Cat. No.: HY-W441011
CAS No.: 1383932-86-2
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
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Cat. No.: HY-140679
CAS No.: 80506-64-5
Purity:  ≥98.0%
Synonyms: mPEG20000-NH2
mPEG20000-amine (mPEG20000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG20000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-101530C
CAS No.: 9004-99-3
Purity:  ≥98.0%
Synonyms: PEG 100 stearate
Polyoxyl 100 stearate (PEG-100 stearate) is a non-ionic surfactant formed by polyethylene glycol (PEG) and stearic acid, and it is commonly used in pharmaceutical preparations, nanocarriers, emulsification systems and cosmetic formulations .
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Cat. No.: HY-P2213
CAS No.: 109053-09-0
Target:  

MMP Apoptosis

Research Areas:  

Cancer

GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .
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Cat. No.: HY-140676
CAS No.: 80506-64-5
Purity:  99.57%
Synonyms: mPEG2000-NH2
mPEG2000-amine (mPEG2000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG2000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-140677
CAS No.: 80506-64-5
Purity:  ≥98.0%
Synonyms: mPEG5000-NH2
mPEG5000-amine (mPEG5000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG5000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-140675
CAS No.: 80506-64-5
Purity:  ≥98.0%
Synonyms: mPEG1000-NH2
mPEG1000-amine (mPEG1000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG1000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-P10739
CAS No.: 1021155-39-4
Target:  

Exosomes Collagen

Research Areas:  

Inflammation/Immunology

WYRGRL is a selective, high-affinity collagen type II-binding peptide with a IC50 of 140 nM. Collagen type II is the most abundant and specific structural protein in the extracellular matrix of articular cartilage. WYRGRL can precisely target small-molecule compounds such as Dexamethasone (HY-14648) and nanocarrier-engineered exosomes to cartilage, significantly enhancing their therapeutic effects on osteoarthritis .
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Cat. No.: HY-172470
DSPE-PEG2000-GE11 is a nanocarrier component composed of DSPE and the EGFR-targeting peptide (GE11). DSPE-PEG2000-GE11 specifically binds to EGFR and mediates receptor-mediated endocytosis of micellar drug carriers. DSPE-PEG2000-GE11 can be used for drug delivery .
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Cat. No.: HY-W441007
CAS No.: 1360858-99-6
DSPE-MAL is a phospholipid compound with a maleimide reactive group. DSPE-MAL contains two saturated fatty acids and can self-assemble in water to form a lipid bilayer. DSPE-MAL can be used to prepare liposomes as nanocarriers for active molecules .
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Cat. No.: HY-143702
CAS No.: 1010076-97-7
Purity:  95.20%
Synonyms: NBD-DOTAP
Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research .
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Cat. No.: HY-W094695
CAS No.: 9005-84-9
Starch soluble is a biodegradable, highly biocompatible hydrophilic biopolymer nanocarrier. Starch soluble forms complexes with iodine, acts on multiple bacterial targets, and improves the storage stability of iodine. Starch soluble enhances the solubility and dissolution rate of Gefitinib (HY-50895). Starch soluble can be used as a nanocarrier for relevant studies .
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Cat. No.: HY-W002879
CAS No.: 269409-70-3
4-Hydroxyphenylboronic acid pinacol ester is a ROS-responsive component. 4-Hydroxyphenylboronic acid pinacol ester can structurally modify hyaluronic acid to prepare ROS-responsive intelligent nanocarriers and compound delivery systems. 4-Hydroxyphenylboronic acid pinacol ester endows hyaluronic acid-based nanocarriers with ROS responsiveness, enabling them to rapidly release the encapsulated Curcumin (HY-N0005) in the presence of reactive oxygen species. 4-Hydroxyphenylboronic acid pinacol ester is applicable to research related to periodontitis. 4-Hydroxyphenylboronic acid pinacol ester can also be used for the synthesis of boronic acid-modified resins .
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Cat. No.: HY-P2314
Target:  

Transferrin Receptor

Research Areas:  

Cancer

HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier .
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Cat. No.: HY-155881
CAS No.: 80506-64-5
Purity:  ≥98.0%
Synonyms: mPEG550-NH2
mPEG550-amine (mPEG550-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG550-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-W440914
CAS No.: 1000788-53-3
DSPE-PEG1000-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. The polymer can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers. . Reagent grade, for research use only.
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Cat. No.: HY-W440914B
CAS No.: 1000788-53-3
DSPE-PEG10000-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG10000-FITC can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers .
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