1010076-97-7
Chemical Structure
Fluorescent DOTAP
Synonym(s): NBD-DOTAP
- CAS No.: 1010076-97-7
- Formula:C36H60ClN5O7
- Molecular Weight:710.34
IUPAC Name: N,N,N-trimethyl-2-((6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoyl)oxy)-3-(oleoyloxy)propan-1-aminium chloride
InChIKey: XDKRQAPVOCOOGF-USGGBSEESA-M
SMILES: CCCCCCCC/C=C\CCCCCCCC(OCC(OC(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C21)=O)C[N+](C)(C)C)=O.[Cl-]
Biological Activity: Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research[1][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fluorescent DOTAP | 95.95% | Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research. | ||||||||||||||||||||
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- [1]. Simberg, D., et al., (2004). DOTAP (and other cationic lipids): chemistry, biophysics, and transfection. Critical reviews in therapeutic drug carrier systems, 21(4), 257-317. [Content Brief]
- [3]. Chen, W., et al., (2008). A simple but effective cancer vaccine consisting of an antigen and a cationic lipid. Cancer immunology, immunotherapy : CII, 57(4), 517-530. [Content Brief]
Keywords
