16:0-06:0 NBD PE
Based on 1 Customer Validation
16:0-06:0 NBD PE (C6-NBD-PE) is a commonly used fluorescent phospholipid analog and membrane-disrupting agent for investigating membrane lipid structure and dynamics. In aqueous buffers, the self-assembly of 16:0-06:0 NBD PE can be disrupted via binding to methylated α-, β-, and γ-cyclodextrins. 16:0-06:0 NBD PE can be selectively extracted from lipid vesicles upon the addition of methylated cyclodextrins, with an extraction efficiency lower than that of NBD-PC and NBD-SM analogs.
For research use only. We do not sell to patients.
- CAS No.: 106918-69-8
- Formula: C33H56N5O11P
- Molecular Weight:729.80
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Methylated α- and β-cyclodextrins (1-10 mM; 300 seconds at 37 °C) are more effective than methylated γ-cyclodextrin at extracting 16:0-06:0 NBD PE from POPC LUVs, with up to ~30% of the analog extracted from the outer leaflet at 10 mM cyclodextrin concentration[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 106918-69-8
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Appearance Solid
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Molecular Weight 729.80
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Formula C33H56N5O11P
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SMILES
NCCOP(OC[C@@H](COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C12)=O)(O)=O
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Synonyms
C6-NBD-PE
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)