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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
olanzapine
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "olanzapine" in MCE Product Catalog:
14
14 Publications Verification
Synonyms: LY170053
Research Areas:
Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptor (Ki=19 nM). Olanzapine is an atypical antipsychotic .
3
3 Cited Publications
Research Areas:
RO5256390 is an orally effective trace amine associated receptor 1 (TAAR1) agonist. RO5256390 exhibits pro-cognitive and antidepressant-like properties in rodent and primate models, showing similar brain activation patterns to Olanzapine (HY-14541). RO5256390 blocks compulsive overeating behavior in rats. RO5256390 can inhibit ATP (HY-B2176)-induced TNF secretion in mouse bone marrow-derived macrophages .
Cat. No.: HY-14541R
CAS No.: 132539-06-1
Synonyms: LY170053 (Standard)
Target:
Reference Standards 5-HT Receptor Dopamine Receptor mAChR Adrenergic Receptor Autophagy Mitophagy Apoptosis
Research Areas:
Olanzapine (Standard) is the analytical standard of Olanzapine. This product is intended for research and analytical applications. Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptor (Ki=19 nM). Olanzapine is an atypical antipsychotic .
Target:
Research Areas:
Olanzapine N-oxide is a compound under investigation for the metabolism of antipsychotic compounds. Olanzapine N-oxidation and N-demethylation are catalyzed by different enzymes, and its plasma concentration and clearance are not affected by a single factor, such as a specific genotype or smoking behavior.
Cat. No.: HY-125446
CAS No.: 174756-45-7
Synonyms: LY-290411; 2-OH-OLZ
Target:
Research Areas:
2-Hydroxymethyl olanzapine is a metabolite and a degradation product of Olanzapine (HY-14541) [1][2].
Synonyms: LY170053-d3
Synonyms: AVE1625
Target:
Research Areas:
Drinabant (AVE1625) is an orally active CB1 receptor antagonist. Drinabant (AVE1625) inhibits the agonist-stimulated calcium signal with IC50 values of 25 nM and 10 nM for the hCB1-R and rCB1-R, respectively, and is ineffective for the hCB2-R .
Cat. No.: HY-W004412
CAS No.: 221176-49-4
Synonyms: LY301664
Target:
Research Areas:
Olanzapine-lactam (LY301664) is a specific impurity of Olanzapine (HY-14541) as well as its potential metabolite .
Cat. No.: HY-W127671
CAS No.: 2537-36-2
Cat. No.: HY-W015773
CAS No.: 138564-58-6
Target:
Research Areas:
2-Amino-5-methylthiophene-3-carbonitrile can be used in the synthesis of Olanzapine (HY-14541) .
Cat. No.: HY-14541A
CAS No.: 783334-36-1
Synonyms: LY170053 hydrochloride
Research Areas:
Olanzapine hydrochloride is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptor (Ki=19 nM). Olanzapine hydrochloride is an atypical antipsychotic .
Cat. No.: HY-Z4466
CAS No.: 1017241-34-7
Target:
Research Areas:
Olanzapine ketolactam (compound 1) is the impurity of Olanzapine (HY-14541). Olanzapine is a selective, orally active monoaminergic antagonist .
Cat. No.: HY-W004412R
CAS No.: 221176-49-4
Synonyms: LY301664 (Standard)
Target:
Research Areas:
Olanzapine-lactam (Standard) (LY301664 (Standard)) is the analytical standard of Olanzapine-lactam (HY-W004412). This product is intended for research and analytical applications. Olanzapine-lactam (LY301664) is a specific impurity of Olanzapine (HY-14541) as well as its potential metabolite .
Cat. No.: HY-Z4467
CAS No.: 1017241-36-9
Target:
Research Areas:
Olanzapine thiolactam (compound 2) is an impurity of Olanzapine .
Cat. No.: HY-14541S1
CAS No.: 1252611-62-3
Synonyms: LY170053-d4
Cat. No.: HY-14541S2
CAS No.: 1093380-13-2
Synonyms: LY170053-d8
Cat. No.: HY-125446S
CAS No.: 1190006-36-0
Synonyms: LY-290411-d3; 2-OH-OLZ-d3
Cat. No.: HY-119393S
CAS No.: 1189732-75-9
Target:
Research Areas:
Olanzapine N-Oxide-d3 is the d3-labeled Olanzapine N-oxide (HY-119393). Olanzapine N-oxide is a phase I metabolite of Olanzapine (HY-14541). Olanzapine N-oxide serves as a substrate for reduction reactions and converts to Olanzapine in whole blood in vitro. Olanzapine is an antipsychotic compound widely used in research on schizophrenia and other psychotic disorders .
Cat. No.: HY-W040976
CAS No.: 138564-60-0
Target:
Research Areas:
Olanzapine impurity 2 hydrochloride is an impurity of Olanzapine hydrochloride.
Cat. No.: HY-W344197
CAS No.: 719300-59-1
Target:
Research Areas:
Olanzapine impurity 3 is an impurity of Olanzapine.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
