783334-36-1
783334-36-1
Chemical Structure
Olanzapine hydrochloride
Synonym(s): LY170053 hydrochloride
- CAS No.: 783334-36-1
- Formula:C17H21ClN4S
- Molecular Weight:348.89
InChIKey: MFURKUWVJOJUHP-UHFFFAOYSA-N
SMILES: CN(CC1)CCN1C2=NC3=C(NC4=C2C=C(C)S4)C=CC=C3.Cl
Biological Activity: Olanzapine hydrochloride is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptor (Ki=19 nM). Olanzapine hydrochloride is an atypical antipsychotic[1][2].
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Olanzapine hydrochloride | Olanzapine hydrochloride is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptor (Ki=19 nM). Olanzapine hydrochloride is an atypical antipsychotic. | |||||||||||||||||||||
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References
Keywords
