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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
oxyanion
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "oxyanion" in MCE Product Catalog:
Cat. No.: HY-W145603
CAS No.: 4630-62-0
Synonyms: Phenyl α-D-Glucoside
Cat. No.: HY-182024
Target:
Research Areas:
SARS-CoV-2 3CLpro-IN-36 is a SARS-CoV-2 3CLpro inhibitor and antiviral agent with a human sub-micromolar IC50 against SARS-CoV-2 3CLpro.SARS-CoV-2 3CLpro-IN-36 forms a covalent bond with catalytic Cys145 of SARS-CoV-2 3CLpro; its tetrazole core occupies the S1 pocket and interacts with His163, while its chloroacetamide carbonyl forms hydrogen bonds with the backbone amides of Gly143 and Ser144 in the oxyanion hole.SARS-CoV-2 3CLpro-IN-36 reduces SARS-CoV-2 replication in infected cells.SARS-CoV-2 3CLpro-IN-36 can be used for the research of SARS-CoV-2 infection .
Cat. No.: HY-184699
AKR1C3-IN-16 is a selective AKR1C3 inhibitor with a human IC50 of 0.084 μM. AKR1C3-IN-16 features a coumarin core that anchors to the oxyanion site and substituents that interact with the SP1 pocket. AKR1C3-IN-16 acts as an antiproliferative agent in prostate cancer cells. AKR1C3-IN-16 can be used for the research of castration-resistant prostate cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
