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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
pathogen defense
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "pathogen defense" in MCE Product Catalog:
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2 Cited Publications
Synonyms: Menadione sodium bisulfite; Vitamin K3 sodium bisulfite
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Menadione bisulfite (sodium) is used as an agent to induce acute oxidative stress, and to function as a plant-defense activator against several pathogens.
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Flavanonols Flavonoids Cercis chinensis Bunge Other Diseases Phenols Polyphenols Plants Compositae Disease Research Fields
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Cat. No.: HY-N11420
CAS No.: 62251-96-1
Cat. No.: HY-122464
CAS No.: 77026-92-7
(±)-Jasmonic acid is an endogenous growth regulator closely related to plant resistance to abiotic stresses, used to activate defense responses to wounding, herbivory, and pathogen attacks. (±)-Jasmonic acid does not play an independent regulatory role, but works in a complex signaling network with other plant hormone signaling pathways. In addition, (±)-Jasmonic acid can also reduce chlorophyll levels in green and etiolated barley leaf segments and inhibit the elongation of rice seedlings .
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Pyrroline-5-carboxylate sodium is a key intermediate in proline anabolism and catabolism. Pyrroline-5-carboxylate sodium plays important roles in plant defense against pathogen invasion, as well as in redox regulation, nucleotide synthesis and other processes in animal cells .
Cat. No.: HY-P2076
CAS No.: 931395-42-5
Synonyms: SGX942
Cat. No.: HY-N1033
CAS No.: 140631-27-2
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12-Hydroxyjasmonic acid is a metabolite of Jasmonic acid (HY-122464A) and an inducer of defense responses. 12-Hydroxyjasmonic acid can be isolated from potato leaflets. During the response of sugar beet plants to Cercospora beticola infection, 12-Hydroxyjasmonic acid is released through deglycosylation of its glucoside form and participates in the Jasmonic acid-mediated defense signaling pathway. 12-Hydroxyjasmonic acid mediates changes in source-sink relationships during pathogen infection, prioritizing the activation of defense processes over growth processes. 12-Hydroxyjasmonic acid serves as a substrate for salicylic acid Glycosyltransferases in tobacco and rice. 12-Hydroxyjasmonic acid can induce leaflet closure in Samanea saman. 12-Hydroxyjasmonic acid acts as a potato tuber-inducing substance. 12-Hydroxyjasmonic acid does not induce protoplast shrinkage in extensor motor cells of Samanea saman. 12-Hydroxyjasmonic acid can be used in studies related to brown spot disease .
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Pyrroline-5-carboxylate is a key intermediate in proline anabolism and catabolism. Pyrroline-5-carboxylate plays important roles in plant defense against pathogen invasion, as well as in redox regulation, nucleotide synthesis and other processes in animal cells .
Cat. No.: HY-P2076A
Synonyms: SGX942 TFA
Cat. No.: HY-131266R
CAS No.: 1657014-33-9
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Menadione bisulfite (sodium) (Standard) is the analytical standard of Menadione bisulfite (sodium). This product is intended for research and analytical applications. Menadione bisulfite (sodium) is used as an agent to induce acute oxidative stress, and to function as a plant-defense activator against several pathogens.
Cat. No.: HY-B1897AR
CAS No.: 130-37-0
Synonyms: Menadione sodium bisulfite (Standard); Vitamin K3 sodium bisulfite (Standard)
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Menadione bisulfite (sodium) (Standard) is the analytical standard of Menadione bisulfite (sodium). This product is intended for research and analytical applications. Menadione bisulfite (sodium) is used as an agent to induce acute oxidative stress, and to function as a plant-defense activator against several pathogens.
Cat. No.: HY-P2291
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Cat. No.: HY-P2291A
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Cat. No.: HY-32350S1
CAS No.: 1261254-46-9
Synonyms: 1α,25-Dihydroxy Vitamin D2-d3
Cat. No.: HY-P11458
Synonyms: Nlp24
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Cat. No.: HY-L175
176 compounds
Inflammasomes are classic pattern recognition receptors for natural immune responses. Inflammasomes are polymeric protein complexes that regulate inflammatory responses and pyrolytic cell death, thereby exerting the host's defense against microorganisms. Inflammasomes sensors are associated with adapter proteins, activating inflammatory caspase-1, releasing inflammatory cytokines and inducing cell death, endowing the host with defense against pathogens. NLRP1, NLRP3, NLRC4, AIM2, and pyrin are considered typical inflammasomes because they convert cysteine asparaginase-1 into catalytically active capsaicin-1. In addition to infectious diseases, the importance of inflammasomes is also related to various clinical diseases, such as autoimmune diseases, neurodegeneration and metabolic disorders, and the development of cancer. Therefore, it is necessary to strictly regulate the activation and function of inflammasomes to avoid accidental host tissue damage while inducing pathogens to kill the inflammatory response.
MCE designs a unique collection of 176 inflammasomes related compounds. It is a good tool to be used for research on Inflammation, cancer and other diseases.
Cat. No.: HY-174525
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Human TLR3 mRNA encodes the human toll like receptor 3 (TLR3) protein, a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR3 recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses.
Cat. No.: HY-L007
8,534 compounds
The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. Inflammation is also the body's attempt at self-protection to remove harmful stimuli and begin the healing process. It’s part of the body's immune response. The immune system recognizes damaged cells, irritants, and pathogens, and inflammation begins the healing process. Inflammatory abnormalities are a large group of disorders that underlie a vast variety of human diseases. The immune system is often involved with inflammatory disorders, demonstrated in both allergic reactions and some myopathies, with many immune system disorders resulting in abnormal inflammation.
MCE designs a unique collection of 8,534 compounds that are useful tool for Immunology/Inflammation research or autoimmune inflammatory diseases drug discovery.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
