Pyrroline-5-carboxylate sodium
Based on 1 Customer Validation
Pyrroline-5-carboxylate sodium is a key intermediate in proline anabolism and catabolism. Pyrroline-5-carboxylate sodium plays important roles in plant defense against pathogen invasion, as well as in redox regulation, nucleotide synthesis and other processes in animal cells.
For research use only. We do not sell to patients.
- Purity: 98.03%
- CAS No.: 72978-16-6
- Formula: C5H6NNaO2
- Molecular Weight:135.10
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Sodium pyrroline-5-carboxylate (0.3-3.0 mM; 1 hour) activates the pentose phosphate pathway in normal human fibroblasts, LLC-RK1 cells and human erythrocytes[1].
Sodium pyrroline-5-carboxylate (1 μM-0.5 mM; 1 hour) increases the level of phosphoribosyl pyrophosphate in human red blood cells[1].
Sodium pyrroline-5-carboxylate (0.5 mM; up to 4 hours) increases the level of PP-ribose-P in serum-starved quiescent human fibroblasts in a time-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 72978-16-6
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Appearance Solid
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Molecular Weight 135.10
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Formula C5H6NNaO2
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Color White to off-white
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SMILES
O=C(C1=NCCC1)O[Na]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 25 mg/mL (185.05 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.4019 mL | 37.0096 mL | 74.0192 mL | 185.0481 mL |
| 5 mM | 1.4804 mL | 7.4019 mL | 14.8038 mL | 37.0096 mL | |
| 10 mM | 0.7402 mL | 3.7010 mL | 7.4019 mL | 18.5048 mL | |
| 15 mM | 0.4935 mL | 2.4673 mL | 4.9346 mL | 12.3365 mL | |
| 20 mM | 0.3701 mL | 1.8505 mL | 3.7010 mL | 9.2524 mL | |
| 25 mM | 0.2961 mL | 1.4804 mL | 2.9608 mL | 7.4019 mL | |
| 30 mM | 0.2467 mL | 1.2337 mL | 2.4673 mL | 6.1683 mL | |
| 40 mM | 0.1850 mL | 0.9252 mL | 1.8505 mL | 4.6262 mL | |
| 50 mM | 0.1480 mL | 0.7402 mL | 1.4804 mL | 3.7010 mL | |
| 60 mM | 0.1234 mL | 0.6168 mL | 1.2337 mL | 3.0841 mL | |
| 80 mM | 0.0925 mL | 0.4626 mL | 0.9252 mL | 2.3131 mL | |
| 100 mM | 0.0740 mL | 0.3701 mL | 0.7402 mL | 1.8505 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Pyrroline-5-carboxylate sodium Related Classifications
HY-138354A Related Classifications
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