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Results for "

polyphenol compound

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (3) Autophagy (1) Bacterial (5) Caspase (1) COX (1) Drug Derivative (2) Endogenous Metabolite (4) Fungal (4) Isotope-Labeled Compounds (1) Liposome (1) MDM-2/p53 (1) NO Synthase (1) Reactive Oxygen Species (ROS) (2) Reference Standards (2) Tyrosinase (1)
By Research Areas:	Cancer (8) Cardiovascular Disease (2) Infection (7) Inflammation/Immunology (6) Metabolic Disease (2) Neurological Disease (2)
Oligonucleotides:	Liposome (1)

Inhibitors & Agonists

Screening Libraries

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N1579

Pyrogallol 4 Publications Verification	Endogenous Metabolite Fungal Apoptosis	Infection
Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.

HY-N0295

Protocatechualdehyde 1 Publications Verification Catechaldehyde; Protocatechuic aldehyde; Rancinamycin IV	Reactive Oxygen Species (ROS) Bacterial Endogenous Metabolite	Infection Cancer
Protocatechualdehyde (Catechaldehyde), a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae, is associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging, an antibacterial and anti-inflammatory agent .

HY-N0521A

(+)-Gallocatechin 1 Publications Verification	Others	Cancer
(+)-Gallocatechin is a polyphenol compound from green tea, possesses anticancer activity .

HY-N1925

Tea polyphenol 2 Publications Verification	Apoptosis Autophagy	Neurological Disease Inflammation/Immunology Cancer
Tea polyphenol is the floorboard of phenolic compounds in tea. Tea polyphenol exhibits biological activity including antioxidant and anti-cancer activities, inhibition of cell proliferation, induction of apoptosis, cell cycle arrest and modulation of carcinogen metabolism .

HY-N1579R

Pyrogallol (Standard)	Reference Standards Endogenous Metabolite Fungal Apoptosis	Infection
Pyrogallol (Standard) is the analytical standard of Pyrogallol. This product is intended for research and analytical applications. Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.

HY-N10668

2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid	Others	Others
2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid (compound 29) is a natural polyphenol compound found in hop bract .

HY-N0521AS

(+)-Gallocatechin-13C3	Isotope-Labeled Compounds	Cancer
(+)-Gallocatechin- ¹³C₃ is the ¹³C-labeled (+)-Gallocatechin. (+)-Gallocatechin is a polyphenol compound from green tea, possesses anticancer activity .

HY-177840

Liposomal Curcumin	Liposome	Inflammation/Immunology
Liposomal Curcumin is a specialized delivery system that encapsulates curcumin within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of curcumin. Curcumin is a polyphenol compound extracted from the

HY-N13117

Pinocembrin 7-O-[4′′,6′′-(S)-HHDP]-β-D-glucoside	Others	Cancer
Pinocembrin 7-O-[4′′,6′′-(S)-HHDP]-β-D-glucoside (compound 3) is a polyphenol that has weak antiproliferative activity in PDGF-induced HSC-T6 cells (IC50: 200 μM) .

HY-N0295R

Protocatechualdehyde (Standard) Catechaldehyde (Standard); Protocatechuic aldehyde (Standard); Rancinamycin IV (Standard)	Reference Standards Reactive Oxygen Species (ROS) Bacterial Endogenous Metabolite	Infection Cancer
Protocatechualdehyde (Standard) is the analytical standard of Protocatechualdehyde. This product is intended for research and analytical applications. Protocatechualdehyde (Catechaldehyde), a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae, is associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging, an antibacterial and anti-inflammatory agent .

HY-174260

Neuroprotective agent 11	NO Synthase COX Caspase MDM-2/p53	Neurological Disease
Neuroprotective agent 11 (Compound 1a) is an orally active polyphenol compound with significant protective effects against cerebral ischemia. The main activities of Neuroprotective agent 11 include inhibiting neuronal inflammation and apoptosis, reducing cerebral infarction volume, and improving behavioral symptoms of cerebral ischemic mice. Neuroprotective agent 11 exerts its regulatory mechanism by downregulating the expression of inflammatory factors (iNOS、COX-2) and apoptotic proteins (cleaved-Caspase3, p53). Neuroprotective agent 11 can be used in the study of cerebral ischemia-related diseases (such as ischemic stroke) .

HY-178055

Tyrosinase-IN-44	Tyrosinase	Others
Tyrosinase-IN-44 (Compound 3) is a Tyrosinase inhibitor with IC₅₀s of 0.47  and 0.53 μM for monophenolase and diphenolase, respectively. Tyrosinase-IN-44 has superior glutathione peroxidase-like catalytic and DPPH radical scavenging activity. Tyrosinase-IN-44 has potent antibrowning activity in banana and apple juices by directly inhibiting polyphenol oxidase (PPO) and offering antioxidant activity. Tyrosinase-IN-44 can be used for redox regulation and food preservation .

HY-N19082

Triphala extract	Others	Inflammation/Immunology
Tecomella undulata extract is a natural antioxidant, digestive aid, and potential anti-aging agent. It is rich in bioactive compounds such as flavonoids, polyphenols, tannins, and vitamin C.

HY-N18803

Grape seed oil	Others	Cardiovascular Disease
Grape seed oil is a natural compound rich in antioxidants and polyphenols. It is a high-quality byproduct extracted from grape seeds and can be used in research on cardiovascular diseases.

HY-N18740

Andrographis paniculata extract	Bacterial	Infection Inflammation/Immunology
The active ingredients in Andrographis paniculata extract include flavonoids, polyphenols, and diterpenoid lactones, such as andrographolide, dehydroandrographolide, and neoandrographolide. These compounds are known for their anti-inflammatory, antioxidant, immune-boosting, antiviral, and antibacterial properties.

HY-N12476

Tenaxin II	Drug Derivative	Others
Tenaxin II (Compound 3) is a flavonoid compound found in the Scutellaria baicalensis Georgi. Flavonoids are a class of plant secondary metabolites with polyphenol structures, possessing antioxidant, anti-inflammatory, antimutagenic and anticarcinogenic properties, as well as the ability to regulate the function of key cellular enzymes .

HY-N18760

Vitex negundo extract	Bacterial	Infection Inflammation/Immunology
Vitex negundo extract is rich in bioactive compounds such as alkaloids, flavonoids, glycosides, volatile oils, triterpenoids, tannins, polyphenols, flavonoids, and iridoid glycosides. Vitex negundo extract possesses anti-inflammatory, antioxidant, antibacterial, and detoxifying properties.

HY-N13001

7-O-Galloylcatechin	Others	Cancer
7-O-Galloylcatechin is a polyphenol compound found in the seeds of Rhynchosia volubilis. 7-O-Galloylcatechin shows antiproliferative activity against cancer cells. 7-O-Galloylcatechin can be used for the research of cancer, such as melanoma .

HY-P2890B

Laccase, Trametes versicolor	Fungal	Metabolic Disease
Laccase, Trametes versicolor (EC 1.10.3.2), is a blue copper oxidase that reduces molecular oxygen to water. Laccase can oxidize polyphenols, methoxylated phenolic compounds, and diamines, but not tyrosine. Laccase's oxidation reaction is a single-electron reaction and produces free radicals.

HY-P2890C

Laccase, Rhus vernicifera	Fungal	Metabolic Disease
Laccase, Trametes versicolor (EC 1.10.3.2), is a blue copper oxidase that reduces molecular oxygen to water. Laccase can oxidize polyphenols, methoxylated phenolic compounds, and diamines, but not tyrosine. Laccase's oxidation reaction is a single-electron reaction and produces free radicals.

HY-116562

DK-139	Drug Derivative	Cancer
DK-139 is a polyphenol compound bearing a cinnamaldehyde scaffol. DK-139 inhibits clonogenic growth of Cisplatin (HY-17394)-resistant human ovarian cancer. DK-139 can be used for the research of Cisplatin-resistant ovarian cancer .

HY-N18732

Terminalia arjuna extract	Others	Cardiovascular Disease
Terminalia arjuna extract is a precious natural compound derived from the bark of the Terminalia arjuna tree, rich in bioactive components such as triterpenoids, flavonoids, tannins, and polyphenols. Terminalia arjuna extract has cardioprotective effects, helping to strengthen the heart muscle, lower cholesterol levels, stabilize blood pressure, and prevent thrombosis.

HY-N19065

Dalchini extract	Bacterial	Infection Inflammation/Immunology
Dalchini extract is rich in various bioactive compounds, including cinnamaldehyde, eugenol, tannins, polyphenols, and aromatic essential oils. Dalchini extract helps regulate blood sugar levels and improve insulin sensitivity. It also possesses anti-inflammatory, antioxidant, and antibacterial properties, which help enhance immune function, prevent infection, and reduce inflammation.

Cat. No.	Product Name

HY-L057

Phenols Library	1,290 compounds
Phenolic compounds are usually referred to as a diverse group of naturally occurring compounds with multiple medical properties, such as antioxidants, antimicrobial properties. Those compounds are commonly found in food and plants. They have high synthetic, medicinal and industrial values. Polyphenols are compounds with multiple phenolic functionalities. Naturally occurring polyphenols are known to have biological activities for use as drugs, for example, in diseases like AIDS, heart ailments, ulcer formation, bacterial infection, mutagenesis and neural disorders. MCE offers a unique collection of 1,290 natural phenol compounds which is a useful tool for drug discovery as an important source of lead compounds.

Phenols Library

1,290 compounds

Phenolic compounds are usually referred to as a diverse group of naturally occurring compounds with multiple medical properties, such as antioxidants, antimicrobial properties. Those compounds are commonly found in food and plants. They have high synthetic, medicinal and industrial values. Polyphenols are compounds with multiple phenolic functionalities. Naturally occurring polyphenols are known to have biological activities for use as drugs, for example, in diseases like AIDS, heart ailments, ulcer formation, bacterial infection, mutagenesis and neural disorders.

MCE offers a unique collection of 1,290 natural phenol compounds which is a useful tool for drug discovery as an important source of lead compounds.

HY-L094

Food-Sourced Compound Library	2,057 compounds
The health benefits deriving from the consumption of certain foods have been common knowledge. All foods are made up of chemical substances. Chemicals in foods are largely harmless and often desirable. At present, numerous researchers have been focused on the beneficial role played by certain food components in the close relationship between food intake and health status. For example, polyphenols, a common class of compounds among foods, are well-known antioxidants, which may play a role in the prevention of several diseases including type 2 diabetes, cardiovascular diseases, and some types of cancer. MCE supplies a unique collection of 2,057 compounds from variety of foods. All compounds are with specific food source(s). MCE Food-Sourced Compound Library is the useful tool to discover molecules with pharmaceutical activity from foods.

Food-Sourced Compound Library

2,057 compounds

The health benefits deriving from the consumption of certain foods have been common knowledge. All foods are made up of chemical substances. Chemicals in foods are largely harmless and often desirable. At present, numerous researchers have been focused on the beneficial role played by certain food components in the close relationship between food intake and health status. For example, polyphenols, a common class of compounds among foods, are well-known antioxidants, which may play a role in the prevention of several diseases including type 2 diabetes, cardiovascular diseases, and some types of cancer.

MCE supplies a unique collection of 2,057 compounds from variety of foods. All compounds are with specific food source(s). MCE Food-Sourced Compound Library is the useful tool to discover molecules with pharmaceutical activity from foods.

HY-L163

FDA-Approved Traditional Chinese Medicine Active Compound Library	308 compounds
Traditional Chinese medicine provides abundant natural resources for medicinal compounds, which are often considered effective and safe for drug discovery. Traditional Chinese medicine is based on the principle of "multiple components, multiple targets, and multiple pathways", and naturally has multiple pharmacological effects. As herbal medicine, the secondary plant metabolites in Chinese herbal medicine play an important role in alleviating many diseases in Traditional medicine and folk use. Therefore, the identification of traditional Chinese medicine derived compounds is also an important process in drug development and a necessary factor in dissecting the overall mechanism of action of traditional Chinese medicine. FDA listed compounds have completed extensive preclinical and clinical studies, exhibiting good biological activity, safety, and bioavailability. MCE designs a unique collection of 308 FDA/EMA/NMPA/PMDA etc-approved traditional Chinese medicine active compounds, including flavonoids, polyphenols, alkaloids, terpenoids, and other structural types. It is a good tool for drug reuse and screening drugs from traditional Chinese medicine sources.

FDA-Approved Traditional Chinese Medicine Active Compound Library

308 compounds

Traditional Chinese medicine provides abundant natural resources for medicinal compounds, which are often considered effective and safe for drug discovery. Traditional Chinese medicine is based on the principle of "multiple components, multiple targets, and multiple pathways", and naturally has multiple pharmacological effects. As herbal medicine, the secondary plant metabolites in Chinese herbal medicine play an important role in alleviating many diseases in Traditional medicine and folk use. Therefore, the identification of traditional Chinese medicine derived compounds is also an important process in drug development and a necessary factor in dissecting the overall mechanism of action of traditional Chinese medicine. FDA listed compounds have completed extensive preclinical and clinical studies, exhibiting good biological activity, safety, and bioavailability.

MCE designs a unique collection of 308 FDA/EMA/NMPA/PMDA etc-approved traditional Chinese medicine active compounds, including flavonoids, polyphenols, alkaloids, terpenoids, and other structural types. It is a good tool for drug reuse and screening drugs from traditional Chinese medicine sources.

Cat. No.	Product Name	Category	Target	Chemical Structure