1. Metabolic Enzyme/Protease
  2. Tyrosinase
  3. Tyrosinase-IN-44

Tyrosinase-IN-44 (Compound 3) is a Tyrosinase inhibitor with IC50s of 0.47  and 0.53 μM for monophenolase and diphenolase, respectively. Tyrosinase-IN-44 has superior glutathione peroxidase-like catalytic and DPPH radical scavenging activity. Tyrosinase-IN-44 has potent antibrowning activity in banana and apple juices by directly inhibiting polyphenol oxidase (PPO) and offering antioxidant activity. Tyrosinase-IN-44 can be used for redox regulation and food preservation.

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Tyrosinase-IN-44

Tyrosinase-IN-44 Chemical Structure

CAS No. : 10200-72-3

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Description

Tyrosinase-IN-44 (Compound 3) is a Tyrosinase inhibitor with IC50s of 0.47  and 0.53 μM for monophenolase and diphenolase, respectively. Tyrosinase-IN-44 has superior glutathione peroxidase-like catalytic and DPPH radical scavenging activity. Tyrosinase-IN-44 has potent antibrowning activity in banana and apple juices by directly inhibiting polyphenol oxidase (PPO) and offering antioxidant activity. Tyrosinase-IN-44 can be used for redox regulation and food preservation[1].

Cellular Effect
Cell Line Type Value Description References
MCF7 GI50
> 50 μM
Compound: 1b
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
[PMID: 27487570]
PC-3 GI50
> 50 μM
Compound: 1b
Cytotoxicity against human PC3 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
[PMID: 27487570]
Masse moléculaire

214.15

Formule

C7H5NSSe

CAS No.
SMILES

[SeH]C1=NC2=CC=CC=C2S1

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation
Références
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Tyrosinase-IN-44 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nom du produit:
Tyrosinase-IN-44
Cat. No.:
HY-178055
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