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Cat. No.: HY-178055

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Tyrosinase-IN-44

Tyrosinase-IN-44 (Compound 3) is a Tyrosinase inhibitor with IC₅₀s of 0.47  and 0.53 μM for monophenolase and diphenolase, respectively. Tyrosinase-IN-44 has superior glutathione peroxidase-like catalytic and DPPH radical scavenging activity. Tyrosinase-IN-44 has potent antibrowning activity in banana and apple juices by directly inhibiting polyphenol oxidase (PPO) and offering antioxidant activity. Tyrosinase-IN-44 can be used for redox regulation and food preservation.

For research use only. We do not sell to patients.

CAS No.: 10200-72-3
Formula: C₇H₅NSSe
Molecular Weight:214.15

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Tyrosinase-IN-44 Chemical Structure

CAS No.: 10200-72-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	GI₅₀	>50 μM Compound: 1b	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 27487570]
PC-3	GI₅₀	>50 μM Compound: 1b	Cytotoxicity against human PC3 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 27487570]

Chemical Information

CAS No. 10200-72-3
Molecular Weight 214.15
Formula C₇H₅NSSe
SMILES

[SeH]C1=NC2=CC=CC=C2S1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Islam A, et al. Thiazole- and Benzothiazole-Based Organoselenium Compounds as Dual-Action Agents: Tyrosinase Inhibitors and Functional Mimics of Glutathione Peroxidase. Inorg Chem. 2025 Sep 15;64(36):18206-18226. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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