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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
pqs quorum sensing pathway
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "pqs quorum sensing pathway" in MCE Product Catalog:
Cat. No.: HY-187556
CAS No.: 2581199-68-8
Antibiofilm agent-23 is a PqsR-targeting agent, iron chelator, biofilm inhibitor, biofilm dispersant, and anti-virulence agent. Antibiofilm agent-23 selectively binds to PqsR, disrupts the pqs quorum sensing pathway, restricts bacterial iron acquisition, induces intracellular iron deficiency, reduces pyocyanin, elastase, and rhamnolipid production, impairs biofilm formation, and disperses mature biofilms. Antibiofilm agent-23 exhibits low cytotoxicity and shows antibacterial synergy with Ciprofloxacin (HY-B0356) in Caenorhabditis elegans infection models. Antibiofilm agent-23 can be used for the research of biofilm-associated Pseudomonas aeruginosa infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
