1 Result for "

rel-AZ5576

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "rel-AZ5576" in MCE Product Catalog:

Cat. No.: HY-111537
CAS No.: 1333468-05-5
Target:  

c-Myc CDK Bcl-2 Family

Research Areas:  

Others

rel-AZ5576 is a selective CDK9 inhibitor with the activity of downregulating Mcl-1 and MYC mRNA transcription and protein expression in diffuse large B-cell lymphoma by inhibiting CDK9, promoting MYC protein turnover, reducing MYC phosphorylation on the stable Ser62 residue and downregulating MYC transcriptional targets, inhibiting the growth of diffuse large B-cell lymphoma cell lines in vitro and in vivo and independent of the cell origin.
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