Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
relaxin
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "relaxin" in MCE Product Catalog:
1
1 Cited Publications
Target:
Áreas de investigación:
AZD5462 is a RXFP1 modulator, can be used for heart failure research. RXFP1 is the cognate receptor for human relaxin, belongs to GPCR family 1c number with anti-fibrotic and anti-inflammatory properties .
Target:
Áreas de investigación:
ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM . ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.
Referencia número: HY-P10728
No. CAS: 1818415-56-3
Target:
Áreas de investigación:
Target:
Áreas de investigación:
RLX-33 is a potent, selective and blood-brain barrier (BBB) penetrant relaxin family peptide 3 (RXFP3) antagonist, also blocks relaxin-3-induced ERK1/2 phosphorylation, with IC50 values of 2.36 μM for RXFP3, 7.82 and 13.86 μM for ERK1 and ERK2 phosphorylation, respectively. RLX-33 can block the stimulation of food intake induced by the RXFP3-selective agonist R3/I5 in rats. RLX-33 can be used for the research of metabolic syndrome .
Referencia número: HY-162401
No. CAS: 2813866-27-0
Target:
Áreas de investigación:
AZ7976 (Compound 42) is a highly selective agonist for the Relaxin Family Peptide Receptor 1 (RXFP1) (pEC50 > 10.5). AZ7976 enhances RXFP1's cAMP signaling through an allosteric mechanism, thereby physiologically increasing heart rate. AZ7976 can be used in the field of cardiovascular disease research .
Referencia número: HY-P4890
No. CAS: 1158181-62-4
Target:
RXFP Receptor Reactive Oxygen Species (ROS) Pyroptosis Caspase Interleukin Related TGF-beta/Smad AMPK Apoptosis
Áreas de investigación:
Referencia número: HY-P4890A
Target:
RXFP Receptor Reactive Oxygen Species (ROS) Pyroptosis Caspase Interleukin Related TGF-beta/Smad AMPK Apoptosis
Áreas de investigación:
Referencia número: HY-111583
No. CAS: 2351104-40-8
Target:
Áreas de investigación:
RXFP3/4 agonist 1 is an agonist of relaxin family peptide 3/4 receptor (RXFP3/4), with EC50s of 82/2 nM, respectivley. RXFP3/4 agonist 1 increases food intake in rats .
Referencia número: HY-P991133
No. CAS: 2969217-22-7
Target:
Áreas de investigación:
Referencia número: HY-174334
No. CAS: 2924765-23-9
Target:
Áreas de investigación:
RXFP1 receptor agonist-9 is a potent RXFP1 agonist with an EC50 of 2.5 μM and Ymax of 65%. RXFP1 receptor agonist-9 exhibits good microsomal stability, reasonable PK and pharmacological activity. RXFP1 receptor agonist-9 can be used to the study of heart failure .
Referencia número: HY-P11619
Target:
Áreas de investigación:
Referencia número: HY-P11625
Target:
Áreas de investigación:
Referencia número: HY-P81496A
Synonyms: INSL3; RLF, RLNL; Insulin-like 3; Leydig insulin-like peptide (Ley-I-L); relaxin-like factor
Referencia número: HY-P70176
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: INSL3; Prepro-INSL3; Prev. RLNL; MGC119819; RLF; Ley-I-L; Insulin-Like 3 (Leydig Cell); Insulin-Like 3 (Leydig Cell), Isoform CRA_a; Leydig Insulin-Like Peptide; Leydig Insulin -Like Hormone; relaxin-Like Factor; relaxin-Like Factor B; Insulin-Like 3; Ins
Referencia número: HY-P992108
No. CAS: 3061442-66-5
Synonyms: RELAX10
Target:
Áreas de investigación:
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
