RLN1/Relaxin-1 Protein, Human (HEK293, His)

The RLN1/Relaxin-1 protein is an important ovarian hormone that cooperates with estrogen to induce birth canal dilation. It plays a vital role in connective tissue remodeling during pregnancy, promoting pubic ligament growth and cervical ripening. RLN1/Relaxin-1 Protein, Human (HEK293, His) is the recombinant human-derived RLN1/Relaxin-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of RLN1/Relaxin-1 Protein, Human (HEK293, His) is 163 a.a., with molecular weight of ~20 kDa.

RLN1, also known as Relaxin-1, is a vital ovarian hormone that collaborates with estrogen, particularly in numerous mammals, to induce the dilation of the birth canal. This hormone plays a crucial role in the remodeling of connective tissues during pregnancy, facilitating the growth of pubic ligaments and the ripening of the cervix. The functional form of RLN1 exists as a heterodimer, comprised of a B chain and an A chain, intricately linked by two disulfide bonds. Through its intricate molecular structure, RLN1 contributes significantly to the intricate processes associated with pregnancy, influencing the adaptive changes in the female reproductive system to support a successful birth.

Human

HEK293

C-His

P04808 (V23-C185)

6013  [NCBI]

Approximately 20 kDa

Greater than 82% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.