Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
202 Results for "
spacer
" in MedChemExpress (MCE) Product Catalog:
Products (202)
202 Results for "spacer" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P0123
CAS No.: 1621717-95-0
2
2 Cited Publications
Synonyms: γ-Aminopropyltriethoxysilane; APTES
Synonyms: N-Methylmorpholine N-Oxide; MMNO; 4-Methylmorpholine 4-oxide
Target:
Research Areas:
4-Methylmorpholine N-oxide (N-Methylmorpholine N-Oxide; MMNO; 4-Methylmorpholine 4-oxide) is an amine oxide ligand and ozonation reagent. 4-Methylmorpholine N-oxide forms coordination complexes with lanthanum (III) nitrate and yttrium (III) nitrate via its nitroso oxygen atom. The metal-ligand bonds are dominated by electrostatic interactions with a small covalent component. 4-Methylmorpholine N-oxide is applicable in ozonation reactions for the synthesis of methyl 9-oxononanoate .
Cat. No.: HY-P3669
CAS No.: 200427-88-9
Target:
Research Areas:
Cat. No.: HY-W110542J
CAS No.: 26570-48-9
Synonyms: PEGDA (MW 700)
Target:
Research Areas:
Melitracen hydrochloride is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5-HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space .
Cat. No.: HY-D1635
CAS No.: 194041-66-2
Synonyms: Biotin-XX-SSE
Target:
Research Areas:
Sulfo-NHS-LC-LC-Biotin (Biotin-XX-SSE), a biotin reagent, is used to label the proteins exposed to the external leaflet of intact exosomes and contains a larger spacer arm between the biotin and amine reactive linker. The size of this linker helps to overcome steric hindrance and increases labeling efficiency at the crowded exosome surface .
Cat. No.: HY-W190796A
CAS No.: 2830214-77-0
Target:
Research Areas:
Mal-PEG3-NH2 TFA is a linear heterobifunctional PEG reagent with a maleimide and an amine. Mal-PEG3-NH2 TFA is a crosslinking reagent with a PEG spacer .
Cat. No.: HY-W021068
CAS No.: 58626-38-3
Target:
Research Areas:
3-Maleimidobenzoic acid N-hydroxysuccinimide ester is used as asymmetric spacers .
Synonyms: spacer Phosphoramidite 18
Target:
Research Areas:
Hexaethylene glycol phosphoramidite (Spacer Phosphoramidite 18) is an amidite reagent for oligonucleotide synthesis. Hexaethylene glycol phosphoramidite can be used as a linker in synthesis of nucleotide chain and qPCR probes .
Cat. No.: HY-W190796
CAS No.: 2170654-70-1
Target:
Research Areas:
Mal-PEG3-NH2 is a linear heterobifunctional PEG reagent with a maleimide and an amine. Mal-PEG3-NH2 is a crosslinking reagent with a PEG spacer .
Cat. No.: HY-W591374
CAS No.: 2348405-93-4
Target:
Research Areas:
DBCO-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility. PNP is a good leaving group.
Cat. No.: HY-W800805
CAS No.: 2295813-15-7
DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Cat. No.: HY-W104848
CAS No.: 17057-04-4
Target:
Research Areas:
4-Maleimidobenzoic acid is a protein crosslinker. 4-Maleimidobenzoic acid can be used to synthesis maleimidobenzoyl spacers .
Target:
Research Areas:
Phe-Lys(Trt)-PAB is a cathepsin B substrate, and a cleavable ADC linker. Phe-Lys(Trt)-PAB acts as a lysosomally cleavable substrate for cysteine protease cathepsin B, with cleavage enabling linked anticancer drug release via self-immolative spacer . Phe-Lys(Trt)-PAB can be used for synthesis of ADCs .
Synonyms: Biotin-(AC5)2-hydrazide
Cat. No.: HY-D2965
CAS No.: 1219603-04-9
Synonyms: SPG1
Cat. No.: HY-W800668
Target:
Research Areas:
(S, R, S)-AHPC-PEG4-NHS ester is a PROTAC linker that incorporatess an E3 ligase ligand with a PEG4 spacer to empower PROTAC medicine chemistry. It is is reactive with amine molecule. PEG4 arm increases the molecule's solubility.
Cat. No.: HY-159860
CAS No.: 2940241-38-1
Synonyms: A10-Lin
IR-117-17 is an ionizable cationic amino lipid, targeting conducting airways of the lung. IR-117-17 could be degraded via esterase cleavage and thus be unlikely to accumulate upon repeated dosing . It can be used in research related to diseases that manifest outside alveolar spaces.
Cat. No.: HY-164303
CAS No.: 1698870-53-9
Research Areas:
Val-Cit-PAB-DEA-Duo-DM is a drug-linker conjugate, which consists of the linker Val-Cit-PAB, the spacer DEA and the ADC toxin Duocarmycin DM (Duo-DM) (HY-130978). Val-Cit-PAB-DEA-Duo-DM can be used for the synthesis of ADC molecule .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
