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  3. 3-Aminopropyltriethoxysilane

3-Aminopropyltriethoxysilane  (Synonyms: γ-Aminopropyltriethoxysilane; APTES)

Cat. No.: HY-D0175 Purity: 99.77%
COA Handling Instructions

3-Aminopropyltriethoxysilane (APTES) acts as a strong glue to immobilize biomolecules such as antibodies and enzymes to silicon and silicon derivatives such as silicon nitride (Si3N4 )) on. 3-Aminopropyltriethoxysilane also acts as a spacer, providing biomolecules with more spatial freedom during immobilization for higher specific activity. 3-Aminopropyltriethoxysilane can form a more stable, sensitive, and highly biocompatible bioanalytical platform by immobilizing biomolecules onto some solid materials, electrode materials, nanomaterials, and nanocomposites.

For research use only. We do not sell to patients.

3-Aminopropyltriethoxysilane Chemical Structure

3-Aminopropyltriethoxysilane Chemical Structure

CAS No. : 919-30-2

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Based on 1 publication(s) in Google Scholar

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  • Biological Activity

  • Purity & Documentation

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Description

3-Aminopropyltriethoxysilane (APTES) acts as a strong glue to immobilize biomolecules such as antibodies and enzymes to silicon and silicon derivatives such as silicon nitride (Si3N4 )) on. 3-Aminopropyltriethoxysilane also acts as a spacer, providing biomolecules with more spatial freedom during immobilization for higher specific activity. 3-Aminopropyltriethoxysilane can form a more stable, sensitive, and highly biocompatible bioanalytical platform by immobilizing biomolecules onto some solid materials, electrode materials, nanomaterials, and nanocomposites[1][2].

In Vitro

3-Aminopropyltriethoxysilane is unstable in aqueous solution (hydrolytically unstable), and its ethoxy group is easily hydrolyzed into ethanol and trienol group[2].
3-Aminopropyltriethoxysilane. At neutral pH, the half-lives of APTES are 56 h (10°C) and 8.4 h (24°C), respectively[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

221.37

Formula

C9H23NO3Si

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

NCCC[Si](OCC)(OCC)OCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (451.73 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5173 mL 22.5866 mL 45.1732 mL
5 mM 0.9035 mL 4.5173 mL 9.0346 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.77%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.5173 mL 22.5866 mL 45.1732 mL 112.9331 mL
5 mM 0.9035 mL 4.5173 mL 9.0346 mL 22.5866 mL
10 mM 0.4517 mL 2.2587 mL 4.5173 mL 11.2933 mL
15 mM 0.3012 mL 1.5058 mL 3.0115 mL 7.5289 mL
20 mM 0.2259 mL 1.1293 mL 2.2587 mL 5.6467 mL
25 mM 0.1807 mL 0.9035 mL 1.8069 mL 4.5173 mL
30 mM 0.1506 mL 0.7529 mL 1.5058 mL 3.7644 mL
40 mM 0.1129 mL 0.5647 mL 1.1293 mL 2.8233 mL
50 mM 0.0903 mL 0.4517 mL 0.9035 mL 2.2587 mL
60 mM 0.0753 mL 0.3764 mL 0.7529 mL 1.8822 mL
80 mM 0.0565 mL 0.2823 mL 0.5647 mL 1.4117 mL
100 mM 0.0452 mL 0.2259 mL 0.4517 mL 1.1293 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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3-Aminopropyltriethoxysilane Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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3-Aminopropyltriethoxysilane
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