3-Aminopropyltriethoxysilane
Based on 2 publication(s) in Google Scholar
3-Aminopropyltriethoxysilane (APTES) acts as a strong glue to immobilize biomolecules such as antibodies and enzymes to silicon and silicon derivatives such as silicon nitride (Si3N4 )) on. 3-Aminopropyltriethoxysilane also acts as a spacer, providing biomolecules with more spatial freedom during immobilization for higher specific activity. 3-Aminopropyltriethoxysilane can form a more stable, sensitive, and highly biocompatible bioanalytical platform by immobilizing biomolecules onto some solid materials, electrode materials, nanomaterials, and nanocomposites.
For research use only. We do not sell to patients.
- Purity: 98.18%
- CAS No.: 919-30-2
- Formula: C9H23NO3Si
- Molecular Weight:221.37
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 3-Aminopropyltriethoxysilane
More
Biological Activity
3-Aminopropyltriethoxysilane is unstable in aqueous solution (hydrolytically unstable), and its ethoxy group is easily hydrolyzed into ethanol and trienol group[2].
3-Aminopropyltriethoxysilane. At neutral pH, the half-lives of APTES are 56 h (10°C) and 8.4 h (24°C), respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 919-30-2
-
Appearance Liquid (Density: 0.94 g/cm3)
-
Molecular Weight 221.37
-
Formula C9H23NO3Si
-
Color Colorless to light yellow
-
SMILES
NCCC[Si](OCC)(OCC)OCC
-
Synonyms
γ-Aminopropyltriethoxysilane; APTES
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
-
Journal Impact Factor
-
Most Recent
-
Spectrochim Acta A Mol Biomol Spectrosc
Machine learning-assisted SERS-based dual-aptamer biosensor for ultrasensitive clinical screening of breast cancer. [Abstract]2025 Jul 2;344(Pt 1):126640. PMID: 40627939 -
Solvent & Solubility
H2O : ≥ 100 mg/mL (451.73 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (616 KB)
- English - EN (616 KB)
- Français - FR (616 KB)
- Deutsch - DE (616 KB)
- Norwegian - NO (616 KB)
- Español - ES (616 KB)
- Swedish - SV (616 KB)
- Italian - IT (616 KB)
- Korean - KR (616 KB)
- Portuguese - PT (616 KB)
-
Handling Instructions (2659 KB)
References
[1]. Saengdee P, et al. Optimization of 3-aminopropyltriethoxysilane functionalization on silicon nitride surface for biomolecule immobilization. Talanta. 2020;207:120305. [Content Brief]
[2]. Vashist SK, et al. Immobilization of antibodies and enzymes on 3-aminopropyltriethoxysilane-functionalized bioanalytical platforms for biosensors and diagnostics. Chem Rev. 2014 Nov 12;114(21):11083-130. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.5173 mL | 22.5866 mL | 45.1732 mL | 112.9331 mL |
| 5 mM | 0.9035 mL | 4.5173 mL | 9.0346 mL | 22.5866 mL | |
| 10 mM | 0.4517 mL | 2.2587 mL | 4.5173 mL | 11.2933 mL | |
| 15 mM | 0.3012 mL | 1.5058 mL | 3.0115 mL | 7.5289 mL | |
| 20 mM | 0.2259 mL | 1.1293 mL | 2.2587 mL | 5.6467 mL | |
| 25 mM | 0.1807 mL | 0.9035 mL | 1.8069 mL | 4.5173 mL | |
| 30 mM | 0.1506 mL | 0.7529 mL | 1.5058 mL | 3.7644 mL | |
| 40 mM | 0.1129 mL | 0.5647 mL | 1.1293 mL | 2.8233 mL | |
| 50 mM | 0.0903 mL | 0.4517 mL | 0.9035 mL | 2.2587 mL | |
| 60 mM | 0.0753 mL | 0.3764 mL | 0.7529 mL | 1.8822 mL | |
| 80 mM | 0.0565 mL | 0.2823 mL | 0.5647 mL | 1.4117 mL | |
| 100 mM | 0.0452 mL | 0.2259 mL | 0.4517 mL | 1.1293 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Powered by Bioz