10563-70-9
10563-70-9
Chemical Structure
Melitracen hydrochloride
- CAS No.: 10563-70-9
- Formula:C21H26ClN
- Molecular Weight:327.89
IUPAC Name: 3-(10,10-dimethylanthracen-9(10H)-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
InChIKey: RADLXCPDUXFGFF-UHFFFAOYSA-N
SMILES: CN(C)CC/C=C1C2=C(C=CC=C2)C(C)(C)C3=CC=CC=C/13.Cl
Biological Activity: Melitracen hydrochloride is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5-HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space[1][2].
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Melitracen hydrochloride | 99.80% | Melitracen hydrochloride is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5-HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space. | ||||||||||||||||||||
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Melitracen hydrochloride (Standard) | ≥98% | Melitracen (hydrochloride) (Standard) is the analytical standard of Melitracen (hydrochloride). This product is intended for research and analytical applications. Melitracen hydrochloride is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5-HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space. | ||||||||||||||||||||
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Melitracen-d6 hydrochloride | Melitracen-d6 (hydrochloride) is the deuterium labeled Melitracen hydrochloride. Melitracen hydrochloride is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5-HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-121778Melitracen -
Similarity Score 0.79
HY-B0527ARAmitriptyline hydrochloride (Standard) -
Similarity Score 0.78
HY-B0740RCyclobenzaprine hydrochloride (Standard) -
Similarity Score 0.78
HY-B0527Amitriptyline -
Similarity Score 0.76
HY-165440Cyclobenzaprine -
Similarity Score 0.73
HY-12394Dothiepin -
Similarity Score 0.73
HY-165378(E)-Dothiepin hydrochloride -
Similarity Score 0.72
HY-B1417Nortriptyline hydrochloride -
Similarity Score 0.72
HY-135096Amitriptyline-d3 hydrochloride -
Explore the MedChemAI to find more analogs
References
- [1]. Xiaoqian Zhou , et al. The Efficacy of Flupentixol-Melitracen in the Adjuvant Therapy of Ulcerative Colitis in the Chinese Population: A Meta-Analysis. Gastroenterol Res Pract. 2019 Feb 28;2019:3480732. [Content Brief]
- [2]. K Shimamoto, et al. Myriatic Effect of 9-(gamma-dimethylamino-propylidene)-10, 10-diemthyl-9, 10-dihydroanthracene Hydrochloride (Melitracen) in Mice and Rats. Acta Sch Med Univ Kioto. 1967 Jul;40(1):38-47. [Content Brief]
