1. Autophagy
    Apoptosis
    Metabolic Enzyme/Protease
  2. Autophagy
    Apoptosis
    Drug Metabolite
  3. Nortriptyline hydrochloride

Nortriptyline hydrochloride (Synonyms: Desmethylamitriptyline hydrochloride)

Cat. No.: HY-B1417 Purity: 99.96%
Handling Instructions

Nortriptyline hydrochloride (Desmethylamitriptyline hydrochloride) is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and used to relieve the symptoms of depression.

For research use only. We do not sell to patients.

Nortriptyline hydrochloride Chemical Structure

Nortriptyline hydrochloride Chemical Structure

CAS No. : 894-71-3

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
50 mg USD 60 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Nortriptyline hydrochloride (Desmethylamitriptyline hydrochloride) is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and used to relieve the symptoms of depression[1].

Molecular Weight

299.84

Formula

C₁₉H₂₂ClN

CAS No.
SMILES

CNCC/C=C1C2=CC=CC=C2CCC3=CC=CC=C\13.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (277.91 mM; Need ultrasonic)

H2O : 7.14 mg/mL (23.81 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3351 mL 16.6756 mL 33.3511 mL
5 mM 0.6670 mL 3.3351 mL 6.6702 mL
10 mM 0.3335 mL 1.6676 mL 3.3351 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (6.94 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (6.94 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (6.94 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.96%

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

NortriptylineDesmethylamitriptylineAutophagyApoptosisDrug MetaboliteInhibitorinhibitorinhibit

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Product Name:
Nortriptyline hydrochloride
Cat. No.:
HY-B1417
Quantity:
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