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(E)-Dothiepin hydrochloride

(Synonyms: (E)-Dosulepin hydrochloride; (E)-Dothep hydrochloride)

(E)-Dothiepin ((E)-Dosulepin;(E)-Dothep) hydrochloride is an antidepressant agent with sedative/anxiolytic activity. (E)-Dothiepin hydrochloride is an inhibitor preferring of noradrenaline uptake than serotonin uptake. (E)-Dothiepin hydrochloride facilitates noradrenergic neurotransmission via inhibiting the neuronal uptake. (E)-Dothiepin hydrochloride is also an antagonist of histamine H1-receptor without cardiotoxicity. (E)-Dothiepin hydrochloride exhibits significant analgesic activity in psychogenic facial pain，idiopathic fibromyalgia syndrome or rheumatoid arthritis.

For research use only. We do not sell to patients.

  • CAS No.: 25627-36-5
  • Formula: C19H22ClNS
  • Molecular Weight:331.90
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • (E)-Dothiepin hydrochloride Chemical Structure
    (E)-Dothiepin hydrochloride Chemical Structure
CAS No.: 25627-36-5
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To place orders, for customer services and technical support, please contact:

609-228-6898
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All Histamine Receptor Isoforms

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  • (E)-Dothiepin hydrochloride Chemical Structure
    (E)-Dothiepin hydrochloride Chemical Structure
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  • (E)-Dothiepin hydrochloride