Poly(ethylene glycol) diacrylate (MW 700)  (Synonyms: PEGDA (MW 700))

Poly(ethylene glycol) diacrylate (PEGDA) (MW 700) is a versatile polymer material that is widely used as a building material for hydrogel scaffolds, especially in the fields of tissue engineering and regenerative medicine. Poly(ethylene glycol) diacrylate (MW 700) mimics the extracellular matrix (ECM), providing support and growth space for cells^[1][2].

Poly(ethylene glycol) diacrylate (MW 700) and cellulose nanofibers (CNF) jointly form a hydrogel scaffold. When the thickness of the scaffold reaches 0.4 mm, its surface is rich in micropores and the pore diameters are mostly between 20 and 50 μm, which is suitable for cell attachment^[2].

Product Properties:
This product is readily soluble in water and can be prepared into hydrogel precursor solutions of varying concentrations. Adding the photoinitiator LAP (HY-44076) to this precursor solution triggers crosslinking upon illumination, yielding a hydrogel with a certain mechanical strength.
Instructions:
1. Dissolve this product at a concentration of 10-20 (w/w)% in pure water or phosphate buffer at room temperature, depending on the intended use. Add 0.1-0.3% (w/w)% LAP photoinitiator to prepare a gel precursor solution.
2. Add the above solution to the mold and refrigerate. Irradiation under 405 nm light for 30-60 seconds will form PEGDA hydrogel.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

700.00 (Average)

(C₂H₄O)ⁿC₆H₆O₃

26570-48-9

Liquid

Colorless to light yellow

O=C(C=C)OCCOC(C=C)=O.[n]

Room temperature in continental US; may vary elsewhere.

• [1]. Haiqing Lin, et al. The Effect of Cross-Linking on Gas Permeability in Cross-Linked Poly(Ethylene Glycol Diacrylate). Macromolecules 2005, 38, 20, 8381-8393.

  [2]. Huang L, et al. Antibacterial poly (ethylene glycol) diacrylate/chitosan hydrogels enhance mechanical adhesiveness and promote skin regeneration. Carbohydr Polym. 2019 Dec 1;225:115110.  [Content Brief]

  [3]. Sun D, et al. Tuning the Poisson's ratio of poly(ethylene glycol) diacrylate/cellulose nanofibril aerogel scaffold precisely for cultivation of bone marrow mesenchymal stem cell. J Biomed Mater Res A. 2023 Apr;111(4):502-513.  [Content Brief]