4-Methylmorpholine N-oxide (Synonyms: N-Methylmorpholine N-Oxide; MMNO; 4-Methylmorpholine 4-oxide)

Cat. No.: HY-Y1101B Purity: 99.95%: Data Sheet
COA

SDS
Handling Instructions
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4-Methylmorpholine N-oxide (N-Methylmorpholine N-Oxide; MMNO; 4-Methylmorpholine 4-oxide) is an amine oxide ligand and ozonation reagent. 4-Methylmorpholine N-oxide forms coordination complexes with lanthanum (III) nitrate and yttrium (III) nitrate via its nitroso oxygen atom. The metal-ligand bonds are dominated by electrostatic interactions with a small covalent component. 4-Methylmorpholine N-oxide is applicable in ozonation reactions for the synthesis of methyl 9-oxononanoate.

For research use only. We do not sell to patients.

4-Methylmorpholine N-oxide Chemical Structure

CAS No. : 7529-22-8

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
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Description

In Vitro

Anhydrous 4-methylmorpholine N-oxide decomposes in ozone for 10 min, is purged with oxygen for 10 min, and is cured at room temperature for 2 h. It can mediate the ozonolysis of methyl oleate in dichloromethane (DCM) at -78 °C to synthesize methyl 9-oxononanoate^[1].
4-Methylmorpholine N-oxide forms a 1:3 coordination complex with lanthanide (III)/yttrium (III) nitrate, and this complex exhibits electrostatic metal-ligand bonding^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

117.15

Formula

C₅H₁₁NO₂

CAS No.

7529-22-8

Appearance

Solid

Color

White to light yellow

SMILES

C[N+]1([O-])CCOCC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 116.67 mg/mL (995.90 mM)

DMSO : 50 mg/mL (426.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	8.5361 mL	42.6803 mL	85.3606 mL
5 mM	1.7072 mL	8.5361 mL	17.0721 mL
10 mM	0.8536 mL	4.2680 mL	8.5361 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.95%

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Data Sheet (274 KB) SDS (466 KB)

COA (251 KB) HNMR (228 KB) LCMS (318 KB)

Handling Instructions (2659 KB)

References

[1]. Wang H, et al. Synthesis of chemically edited derivatives of the endogenous regulator of inflammation 9-PAHSA. J Antibiot (Tokyo). 2019;72(6):498-506. [Content Brief]

[2]. Bezerra R F, et al. Addition compounds between 4-methylmorpholine-N-oxide (MMNO) and some lanthanides (III) and yttrium (III) nitrates[J]. Journal of alloys and compounds, 2002, 344(1-2): 120-122.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	8.5361 mL	42.6803 mL	85.3606 mL	213.4016 mL
	5 mM	1.7072 mL	8.5361 mL	17.0721 mL	42.6803 mL
	10 mM	0.8536 mL	4.2680 mL	8.5361 mL	21.3402 mL
	15 mM	0.5691 mL	2.8454 mL	5.6907 mL	14.2268 mL
	20 mM	0.4268 mL	2.1340 mL	4.2680 mL	10.6701 mL
	25 mM	0.3414 mL	1.7072 mL	3.4144 mL	8.5361 mL
	30 mM	0.2845 mL	1.4227 mL	2.8454 mL	7.1134 mL
	40 mM	0.2134 mL	1.0670 mL	2.1340 mL	5.3350 mL
	50 mM	0.1707 mL	0.8536 mL	1.7072 mL	4.2680 mL
	60 mM	0.1423 mL	0.7113 mL	1.4227 mL	3.5567 mL
	80 mM	0.1067 mL	0.5335 mL	1.0670 mL	2.6675 mL
	100 mM	0.0854 mL	0.4268 mL	0.8536 mL	2.1340 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

4-Methylmorpholine N-oxide Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Methylmorpholine N-oxide7529-22-8N-Methylmorpholine N-Oxide MMNO 4-Methylmorpholine 4-oxideBiochemical Assay ReagentsP2/c space groupozonolysiscoordination complexesmethyl oleatenitrosyl oxygen atomyttrium(III) nitratesspace grouplanthanide(III) nitratesmonoclinic space groupmethyl 9-oxononanoateInhibitorinhibitorinhibit

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4-Methylmorpholine N-oxide (Synonyms: N-Methylmorpholine N-Oxide; MMNO; 4-Methylmorpholine 4-oxide)

4-Methylmorpholine N-oxide Related Antibodies

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