2 Results for "

spontaneous lupus

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "spontaneous lupus" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-131968
CAS No.: 1771691-34-9
Purity:  99.92%
BMS-986202 is a potent, selective and orally active Tyk2 inhibitor that binds to Tyk2 JH2 with an IC50 value of 0.19 nM and a Ki of 0.02 nM. BMS-986202 is remarkably selective over other kinases including Jak family members. BMS-986202 is also a weak inhibitor of CYP2C19 with an IC50 value of 14 μM. BMS-986202 can be used for IL-23-driven acanthosis, anti-CD40-induced colitis, and spontaneous lupus research. BMS-986202 is a de novo deuterium .
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Cat. No.: HY-119805
CAS No.: 87545-58-2
Target:  

Others

Research Areas:  

Inflammation/Immunology

YM 13650 is an orally active anti-nephritic agent. YM 13650 exhibits dose-dependent preventive and therapeutic effects in both the rat immune complex nephritis model and the mouse spontaneous lupus nephritis model. YM 13650 can inhibit the increase in urinary protein, improve serum cholesterol and urea nitrogen levels, alleviate renal pathological damage, and prolong the survival time of mice. YM 13650 can be used in the research of nephritic diseases .
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