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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
135 Results for "
thiol reaction
" in MedChemExpress (MCE) Product Catalog:
Products (135)
135 Results for "thiol reaction" in MCE Product Catalog:
21
21 Publications Verification
Cat. No.: HY-W011500
CAS No.: 51805-45-9
Synonyms: Tris(2-carboxyethyl)phosphine hydrochloride
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TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry .
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6 Cited Publications
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RT-AM is a pro-agent real thiol. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.
3
3 Cited Publications
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N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .
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1
1 Cited Publications
Cat. No.: HY-W011500S
CAS No.: 1174025-33-2
Cat. No.: HY-138525
CAS No.: 2720615-82-5
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Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Thiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-107783
CAS No.: 185332-92-7
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Sulfo-GMBS is a crosslinker widely used in chemical modification and coupling reactions of proteins and peptides. Among amine-thiol crosslinkers, Sulfo-GMBS generates the largest number of crosslinks and covers most of the crosslinks identified by AMAS and GMBS .
Cat. No.: HY-D1590
CAS No.: 929679-22-1
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ODIPY Green 8-P2M is a novel thiol-reactive fluorescence probe based on the BODIPY fluorophore, the fluorescence is strongly quenched by d-PeT and then can be restored after reaction with thiol, resulting in an extremely high signal-to-noise ratio. ODIPY Green 8-P2M can be useful for detecting extremely low concentrations of protein in the gel after SDS-PAGE .
Cat. No.: HY-174965C
Synonyms: DBCO-PEG-thiol (MW 2000)
Cat. No.: HY-D1262
CAS No.: 1808174-52-8
Synonyms: thiol-green 2
Cat. No.: HY-W591476B
CAS No.: 134874-49-0
Synonyms: mPEG750-SH
Cat. No.: HY-W872575
CAS No.: 1914971-04-2
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TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
Cat. No.: HY-W019828
CAS No.: 762-72-1
Synonyms: Trimethyl-prop-2-enylsilane
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Allyltrimethylsilane (Trimethyl-prop-2-enylsilane) is an organosilicon compound. Allyltrimethylsilane undergoes photochemical thiol-ene reactions with thiolated soybean oil. Allyltrimethylsilane participates in carbon-carbon bond formation via allylation reactions with acetals, ketals, aldehydes and ketones, forms cyclopropane through reaction with aldehydes, and reacts with iodine to produce trimethylsilyl iodide. Allyltrimethylsilane is applicable to research related to organic synthesis .
Synonyms: AMD473; ZD0473
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Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA .
Cat. No.: HY-156392
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TCO4-PEG7-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG7-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
Cat. No.: HY-E70264
CAS No.: 799812-86-5
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16:0 Coenzyme A triammonium is palmitoyl-CoA, which can serve as a reaction substrate to transfer the palmitoyl group to the free thiol group of the target protein through palmitoylation catalyzed by protein acyl transferases (PATs) .
Cat. No.: HY-W591476D
CAS No.: 134874-49-0
Synonyms: mPEG350-SH
Cat. No.: HY-W800787
CAS No.: 384847-49-8
18:1 PE MCC is a reactive phospholipid containing a maleimide group. 18:1 PE MCC forms covalent bonds with thiol-modified chondroitin sulfate (CS) via thiol-maleimide reaction, and anchors CS to the surface of lipid membranes. 18:1 PE MCC is applicable to glycocalyx model construction and lipid membrane biophysics research .
Cat. No.: HY-118112
CAS No.: 64191-06-6
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4-N-Maleimidobenzoicacid-NHS is a PEG linker that finds utility in bioconjugation endeavors and protein labeling ventures. Specifically designed for selective reaction with thiol groups, the maleimide group establishes covalent linkages, thereby facilitating the coupling of proteins, peptides, or diverse molecules to thiol-bearing biomolecules. The NHS ester is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic conditions to form a covalent bond.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
