2720615-82-5
Chemical Structure
Azido-PEG4-Thiol
- CAS No.: 2720615-82-5
- Formula:C10H21N3O4S
- Molecular Weight:279.36
IUPAC Name: 14-azido-3,6,9,12-tetraoxatetradecane-1-thiol
InChIKey: WXJHTWKPNRQSLU-UHFFFAOYSA-N
SMILES: SCCOCCOCCOCCOCCN=[N+]=[N-]
Biological Activity: Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-Thiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azido-PEG4-Thiol | Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG4-Thiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords