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Results for "

zidovudine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (3) DNA/RNA Synthesis (4) Drug Metabolite (4) HBV (3) HIV (16) HIV Protease (1) Isotope-Labeled Compounds (5) Nucleoside Antimetabolite/Analog (1) Reactive Oxygen Species (ROS) (3) Reference Standards (1) Reverse Transcriptase (2)
By Research Areas:	Cancer (5) Infection (15) Inflammation/Immunology (1)
Click Chemistry:	Azide (5)

Inhibitors & Agonists

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17413

*Zidovudine* 5+ Cited Publications Azidothymidine; AZT; ZDV	HIV	Infection Cancer
Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-137522

Zidovudine O-β-D-glucuronide sodium 3'-Azido-3'-deoxythymidine β-D-glucuronide sodium	Drug Metabolite	Others
Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the glucuronide conjugate and metabolite of Zidovudine (HY-17413), which can be used to detect UGT2B7 activity. As a substrate, Zidovudine O-β-D-glucuronide sodium undergoes deconjugation via hydrolysis by immobilized β-glucuronidase to produce Zidovudine .

HY-116364B

AZT triphosphate tetraammonium 3'-Azido-3'-deoxythymidine-5'-triphosphate tetraammonium	HIV DNA/RNA Synthesis HBV Reactive Oxygen Species (ROS) Apoptosis	Infection
AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) tetraammonium is an active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate tetraammonium exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate tetraammonium also inhibits the DNA polymerase of HBV. AZT triphosphate tetraammonium activates the mitochondria-mediated apoptosis pathway .

HY-106850

3′-Azido-2′,3′-dideoxyuridine AzdU; AzddU; CS-87	HIV	Infection
3′-Azido-2′,3′-dideoxyuridine (AzdU) is a nucleoside analog of Zidovudine (HY-17413). 3′-Azido-2′,3′-dideoxyuridine is a potent inhibitor of human immunodeficiency virus (HIV) replication in human peripheral blood mononuclear cells (PBMC) with limited toxicity for human bone marrow cells (BMC) . 3′-Azido-2′,3′-dideoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-17413R

Zidovudine (Standard) Azidothymidine (Standard); AZT (Standard); ZDV (Standard)	Reference Standards HIV	Infection Cancer
Zidovudine (Standard) is the analytical standard of Zidovudine. This product is intended for research and analytical applications. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-17413S

Zidovudine-d3 Azidothymidine-d₃; AZT-d₃; ZDV-d₃	Isotope-Labeled Compounds HIV	Infection Cancer
Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-17413S2

Zidovudine-d4 Azidothymidine-d₄; AZT-d₄; ZDV-d₄	Isotope-Labeled Compounds HIV	Infection Cancer
Zidovudine-d₄ is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-17413S1

Zidovudine-13C,d3 Azidothymidine-¹³C,d₃; AZT-¹³C,d₃; ZDV-¹³C,d₃	Isotope-Labeled Compounds HIV	Infection Cancer
Zidovudine- ¹³C,d₃ is the ¹³C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-116364

AZT triphosphate 3'-Azido-3'-deoxythymidine-5'-triphosphate	HIV DNA/RNA Synthesis HBV Reactive Oxygen Species (ROS) Apoptosis	Infection
AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate also inhibits the DNA polymerase of HBV. AZT triphosphate activates the mitochondria-mediated apoptosis pathway .

HY-137522S

Zidovudine O-β-D-glucuronide-d3 sodium 3'-Azido-3'-deoxythymidine β-D-glucuronide-d3 sodium	Isotope-Labeled Compounds Drug Metabolite	Others
Zidovudine O-β-D-glucuronide-d₃ sodium (3'-Azido-3'-deoxythymidine β-D-glucuronide-d₃ sodium) is a deuterium labeled Zidovudine O-β-D-glucuronide sodium (HY-137522). Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the glucuronide conjugate and metabolite of Zidovudine (HY-17413), which can be used to detect UGT2B7 activity. As a substrate, Zidovudine O-β-D-glucuronide sodium undergoes deconjugation via hydrolysis by immobilized β-glucuronidase to produce Zidovudine .

HY-116364A

AZT triphosphate TEA 3'-Azido-3'-deoxythymidine-5'-triphosphate TEA	HIV DNA/RNA Synthesis HBV Reactive Oxygen Species (ROS) Apoptosis	Infection
AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) TEA is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TEA exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate TEA also inhibits the DNA polymerase of HBV. AZT triphosphate TEA activates the mitochondria-mediated apoptosis pathway .

HY-137522A

Zidovudine O-β-D-glucuronide 3'-Azido-3'-deoxythymidine β-D-glucuronide	Drug Metabolite	Others
Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) is the glucuronide conjugate and metabolite of Zidovudine (HY-17413), which can be used to detect UGT2B7 activity. As a substrate, Zidovudine O-β-D-glucuronide undergoes deconjugation via hydrolysis by immobilized β-glucuronidase to produce Zidovudine .

HY-126781

Fozivudine tidoxil BM-211290	HIV DNA/RNA Synthesis	Infection
Fozivudine tidoxil (BM-211290) is an orally active thioether lipid-zidovudine (ZDV) conjugate with anti-HIV activity. Fozivudine tidoxil, a member of the NRTI family of agent, is incorporated into the newly synthesized strand of DNA during intracellular viral replication and irreversibly binds viral RT which disrupts viral reverse-transcription . Fozivudine tidoxil is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-105232

AZT-P-ddI IVX-E-59	HIV	Infection
AZT-P-ddI is an antiviral heterodimer composed of Zidovudine (AZT) (HY-17413) and Didanosine (ddI) (HY-B0249). AZT-P-ddI shows inhibitory effect against HIV-1 with an EC₅₀ of 0.14 nM. AZT-P-ddI can be used for the research of infection .

HY-105097

Atevirdine mesylate U 87201E mesylate	HIV Reverse Transcriptase	Inflammation/Immunology
Atevirdine (U 87201E) mesylate is a nonnucleoside reverse transcriptase (NNRT) inhibitor. Atevirdine mesylate can inhibit human immunodeficiency virus type 1 (HIV-1) with an IC₅₀ of 0.06-1.6 μM. Atevirdine mesylate shows highly synergistic effects against Zidovudine/Didanosine-resistant clinical isolates of HIV-1 companied with Zidovudine (HY-17413)/Didanosine (Hy-B0249). Atevirdine mesylate can be used for the research of AIDS .

HY-105098B

(±)-Lobucavir (±)-BMS-180194; SQ 33054	Nucleoside Antimetabolite/Analog	Others
(±)-Lobucavir ((±)-BMS-180194) is a nucleoside analog with carcinogenic activity. In mice, chronic administration of (±)-Lobucavir resulted in tumor formation with a tumor spectrum similar to that observed after chronic administration of zidovudine or ganciclovir.

HY-122268

QYL-685	HIV	Infection
QYL-685 is a Z-methenylcyclopropane nucleoside analog containing 2,6-diaminopurine, which has strong antiviral activity against HIV-1. QYL-685 showed activity against Zidovudine (HY-17413) resistant and Didanosine (HY-B0249) resistant HIV-1 infected clones in vitro. QYL-685 can be used for the study of HIV-1 infection .

HY-167716

Zidovudine diphosphate	HIV	Infection
Zidovudine diphosphate is an antiretroviral agent that exhibits the activity of inhibiting the reverse transcriptase enzyme used by HIV to synthesize DNA, thereby preventing the formation of viral DNA.

HY-137522AS1

Zidovudine Glucuronide-13C6 3'-Azido-3'-deoxythymidine β-D-glucuronide-¹³C₆	Isotope-Labeled Compounds Drug Metabolite	Others
Zidovudine Glucuronide- ¹³C₆ (3'-Azido-3'-deoxythymidine β-D-glucuronide- ¹³C₆) is ¹³C labeled Zidovudine O-β-D-glucuronide. Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection .

HY-19493

Niglizin	Reverse Transcriptase HIV	Infection
Niglizin is a noncompetitive inhibitor of reverse transcriptase. Niglizin can effectively suppress the HIV replication and shows synergetic effect companied with Zidovudine (HY-17413). Niglizin can be used for the research of HIV infection .

HY-19281

DMP-851	HIV Protease HIV	Infection
DMP-851 is a cyclic urea HIV protease inhibitor, with a K_i of 0.021 nM. DMP-851 shows antiviral activity against laboratory strains of HIV-l and HIV-2 as well as against primary clinical isolates derived from Zidovudine (HY-17413)-resistant samples (A018C, E, WR 10983) .

Cat. No.	Product Name	Chemical Structure

HY-17413S

Zidovudine-d3
Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-17413S2

Zidovudine-d4
Zidovudine-d₄ is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-17413S1

Zidovudine-13C,d3
Zidovudine- ¹³C,d₃ is the ¹³C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-137522S

Zidovudine O-β-D-glucuronide-d3 sodium
Zidovudine O-β-D-glucuronide-d₃ sodium (3'-Azido-3'-deoxythymidine β-D-glucuronide-d₃ sodium) is a deuterium labeled Zidovudine O-β-D-glucuronide sodium (HY-137522). Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the glucuronide conjugate and metabolite of Zidovudine (HY-17413), which can be used to detect UGT2B7 activity. As a substrate, Zidovudine O-β-D-glucuronide sodium undergoes deconjugation via hydrolysis by immobilized β-glucuronidase to produce Zidovudine .

Zidovudine O-β-D-glucuronide-d3 sodium

Zidovudine O-β-D-glucuronide-d₃ sodium (3'-Azido-3'-deoxythymidine β-D-glucuronide-d₃ sodium) is a deuterium labeled Zidovudine O-β-D-glucuronide sodium (HY-137522). Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the glucuronide conjugate and metabolite of Zidovudine (HY-17413), which can be used to detect UGT2B7 activity. As a substrate, Zidovudine O-β-D-glucuronide sodium undergoes deconjugation via hydrolysis by immobilized β-glucuronidase to produce Zidovudine .

HY-137522AS1

Zidovudine Glucuronide-13C6
Zidovudine Glucuronide- ¹³C₆ (3'-Azido-3'-deoxythymidine β-D-glucuronide- ¹³C₆) is ¹³C labeled Zidovudine O-β-D-glucuronide. Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection .

Cat. No.	Product Name		Classification

HY-137522

Zidovudine O-β-D-glucuronide sodium 3'-Azido-3'-deoxythymidine β-D-glucuronide sodium		Azide
Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the glucuronide conjugate and metabolite of Zidovudine (HY-17413), which can be used to detect UGT2B7 activity. As a substrate, Zidovudine O-β-D-glucuronide sodium undergoes deconjugation via hydrolysis by immobilized β-glucuronidase to produce Zidovudine .

HY-106850

3′-Azido-2′,3′-dideoxyuridine AzdU; AzddU; CS-87		Azide
3′-Azido-2′,3′-dideoxyuridine (AzdU) is a nucleoside analog of Zidovudine (HY-17413). 3′-Azido-2′,3′-dideoxyuridine is a potent inhibitor of human immunodeficiency virus (HIV) replication in human peripheral blood mononuclear cells (PBMC) with limited toxicity for human bone marrow cells (BMC) . 3′-Azido-2′,3′-dideoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-17413S

Zidovudine-d3 Azidothymidine-d₃; AZT-d₃; ZDV-d₃		Azide
Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-17413S1

Zidovudine-13C,d3 Azidothymidine-¹³C,d₃; AZT-¹³C,d₃; ZDV-¹³C,d₃		Azide
Zidovudine- ¹³C,d₃ is the ¹³C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-126781

Fozivudine tidoxil BM-211290		Azide
Fozivudine tidoxil (BM-211290) is an orally active thioether lipid-zidovudine (ZDV) conjugate with anti-HIV activity. Fozivudine tidoxil, a member of the NRTI family of agent, is incorporated into the newly synthesized strand of DNA during intracellular viral replication and irreversibly binds viral RT which disrupts viral reverse-transcription . Fozivudine tidoxil is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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