210355-14-9
Chemical Structure
QYL-685
- CAS No.: 210355-14-9
- Formula:C20H24N7O5P
- Molecular Weight:473.42
IUPAC Name: methyl ((((Z)-2-((2,6-diamino-9H-purin-9-yl)methylene)cyclopropyl)methoxy)(phenoxy)phosphoryl)-L-alaninate
InChIKey: XHUFBJWIETZGNX-QUADACEYSA-N
SMILES: C[C@H](NP(OC1=CC=CC=C1)(OCC2/C(C2)=C\N3C=NC4=C(N=C(N=C34)N)N)=O)C(OC)=O
Biological Activity: QYL-685 is a Z-methenylcyclopropane nucleoside analog containing 2,6-diaminopurine, which has strong antiviral activity against HIV-1. QYL-685 showed activity against Zidovudine (HY-17413) resistant and Didanosine (HY-B0249) resistant HIV-1 infected clones in vitro. QYL-685 can be used for the study of HIV-1 infection[1].
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QYL-685 | QYL-685 is a Z-methenylcyclopropane nucleoside analog containing 2,6-diaminopurine, which has strong antiviral activity against HIV-1. QYL-685 showed activity against Zidovudine (HY-17413) resistant and Didanosine (HY-B0249) resistant HIV-1 infected clones in vitro. QYL-685 can be used for the study of HIV-1 infection. | |||||||||||||||||||||
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Keywords
