121135-53-3
Chemical Structure
AZT-P-ddI
Synonym(s): IVX-E-59
- CAS No.: 121135-53-3
- Formula:C20H24N9O9P
- Molecular Weight:565.43
IUPAC Name: ((2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl (((2S,5R)-5-(6-oxo-3,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl) hydrogen phosphate
InChIKey: XURFYCWNUGWGDL-VQJWOFKYSA-N
SMILES: O=C1C2=C(NC=N1)N([C@@H]3O[C@@H](CC3)COP(OC[C@@H]4[C@H](C[C@H](N5C(NC(C(C)=C5)=O)=O)O4)N=[N+]=[N-])(O)=O)C=N2
Biological Activity: AZT-P-ddI is an antiviral heterodimer composed of Zidovudine (AZT) (HY-17413) and Didanosine (ddI) (HY-B0249). AZT-P-ddI shows inhibitory effect against HIV-1 with an EC50 of 0.14 nM. AZT-P-ddI can be used for the research of infection[1].
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AZT-P-ddI | AZT-P-ddI is an antiviral heterodimer composed of Zidovudine (AZT) (HY-17413) and Didanosine (ddI) (HY-B0249). AZT-P-ddI shows inhibitory effect against HIV-1 with an EC50 of 0.14 nM. AZT-P-ddI can be used for the research of infection. | |||||||||||||||||||||
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Keywords
