KRH-1636
KRH-1636 is a CXC chemokine receptor (CXCR) 4 antagonist. KRH-1636 can be used in HIV-1 research.
For research use only. We do not sell to patients.
- CAS No.: 568526-77-2
- Formula: C32H37N7O2
- Molecular Weight:551.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
CXCR4 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | CC50 |
400 μM
Compound: KRH-1636
|
Cytotoxicity against human MT4 cells assessed as reduction in cell viability
Cytotoxicity against human MT4 cells assessed as reduction in cell viability
|
[PMID: 29500940] |
| MT4 | CC50 |
80 μM
Compound: KRH-1636
|
Cytotoxicity against human MT4 cells assessed as reduction of cell viability
Cytotoxicity against human MT4 cells assessed as reduction of cell viability
|
[PMID: 22579418] |
| MT4 | EC50 |
0.33 μM
Compound: KRH-1636
|
Antiviral activity against X4-tropic HIV1 NL4.3 infected in human MT4 cells assessed as protection from virus-induced cytopathogenicity
Antiviral activity against X4-tropic HIV1 NL4.3 infected in human MT4 cells assessed as protection from virus-induced cytopathogenicity
|
[PMID: 22579418] |
Chemical Information
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CAS No. 568526-77-2
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Molecular Weight 551.68
-
Formula C32H37N7O2
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SMILES
O=C(N[C@H](C(N[C@H](C1=C2C=CC=CC2=CC=C1)C)=O)CCCNC(N)=N)C3=CC=C(CNCC4=NC=CC=C4)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)