ATRN - attractin Gene

Also Known as MGCA; DPPT-L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8455

About ATRN

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:3,471,018-3,651,118 (from NCBI)

This gene has 2 transcripts (splice variants), 209 orthologues and 27 paralogues. Ubiquitous expression in duodenum (RPKM 20.8), thyroid (RPKM 17.2) and 25 other tissues.

Summary

This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016]

ATRN Products (4)

mRNA Protein Name
NM_001207047.3 NP_001193976.1 attractin isoform 4
NM_001323332.2 NP_001310261.1 attractin isoform 5 precursor
NM_139321.3 NP_647537.1 attractin isoform 1 preproprotein
NM_139322.4 NP_647538.1 attractin isoform 2 preproprotein

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
17261078 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ATRN Protein Structure

CUB

CUB: CUB domain (132 - 245)

Kelch_1

Kelch_1: Kelch motif (340 - 380)

Kelch_4

Kelch_4: Galactose oxidase, central domain (501 - 548)

Kelch_4

Kelch_4: Galactose oxidase, central domain (554 - 605)

Lectin_C

Lectin_C: Lectin C-type domain (806 - 920)

PSI

PSI: Plexin repeat (986 - 1061)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1429 a.a.
Protein Preferred Names Protein Names

attractin

  • attractin-2

Related Diseases

Diseases Alias
Kidney Cortex Necrosis

  • Renal Cortical Necrosis
Seborrheic Dermatitis

  • Seborrhoeic Dermatitis

  • Seborrhea

  • Seborrhoeic Eczema

  • Skin Seborrheic

  • Dermatitis, Seborrheic
External Ear Disease

  • Diseases Of External Ear

  • Preauricular Cyst

  • Preauricular Sinus And Fistula

  • Preauricular Sinus Or Fistula
Otitis Externa

  • Swimmer'S Ear

  • Infective Otitis Externa

  • Acute Infective Otitis Externa
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01250 ATRN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ATRN VGNC VGNC:68790
Macaca mulatta ATRN VGNC VGNC:70194
Rattus norvegicus ATRN RGD RGD:69063
Canis familiaris ATRN VGNC VGNC:38295
Bos taurus ATRN VGNC VGNC:26335
Mus musculus ATRN MGD MGI:1341628
Others ATRN NCBI