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NDM-1-IN-13
0 ImagesCat. No.: HY-183935NDM-1-IN-13 is a NDM-1 inhibitor with an IC50 of 3.27 μM. As an Antibiotic synergist, NDM-1-IN-13 synergistically reduces the minimum inhibitory concentration of Meropenem (HY-13678) against NDM-1-positive bacterial isolates. NDM-1-IN-13 can be used in studies related to NDM-1-positive bacterial infections. -
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Calcimycin hemimagnesium
0 ImagesCat. No.: HY-N6687BCAS No.: 72124-77-7Synonyms: A-23187 hemimagnesium; Antibiotic A-23187 hemimagnesiumCalcimycin (A-23187) hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemimagnesium induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemimagnesium inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemimagnesium also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemimagnesium induces apoptosis and autophagy. -
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Phthalaldehyde-d4
0 ImagesCat. No.: HY-W012669SCAS No.: 2897613-53-3Synonyms: Phthaldialdehyde-d4Phthalaldehyde-d4 (Phthaldialdehyde-d4) is the deuterium labeled Phthalaldehyde (HY-W012669). Phthalaldehyde reacts with proteins containing primary amines and blocked amino-terminal peptides of amino acids. Phthalaldehyde stabilizes bacterial outer membranes and cell walls, increases the optical density of bacterial cell suspensions, and inhibits bacterial lysis induced by ethylenediaminetetraacetic acid and sodium dodecyl sulfate. Phthalaldehyde exhibits bactericidal activity against Gram-negative vegetative bacteria. -
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Erythromycin (gluceptate)
0 ImagesCat. No.: HY-B0220BCAS No.: 23067-13-2Erythromycin gluceptate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin gluceptate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin gluceptate also exhibits antitumor and neuroprotective effect in different fields of research[3][4]. -
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CZEN-002
0 ImagesCat. No.: HY-P10693CAS No.: 942626-41-7CZEN-002 is a derivative of alpha-melanocyte-stimulating hormone that has anti-inflammatory and antibacterial properties, inhibiting the production of TNF-α. -
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1-Heptadecene
0 ImagesCat. No.: HY-W540874CAS No.: 6765-39-51-Heptadecene is a metabolite found in Aporosa cardiosperma. 1-Heptadecene has antifungal and antibacterial activities. -
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- KN-17
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- P6P-10,10
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β-Gal-NONOate
0 ImagesCat. No.: HY-130570CAS No.: 357192-77-9Beta-gal-nonoate is a β-galactosidase dependent nitric oxide (NO) donor that releases NO once activated by β-galactosidase. β-Gal-NONOate has bactericidal activity and can be used as a bactericide . -
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2(5H)-Furanone (Standard)
0 ImagesSynonyms: γ-Crotonolactone (Standard)2(5H)-Furanone (Standard) is the analytical standard of 2(5H)-Furanone. This product is intended for research and analytical applications. 2(5H)-Furanone (γ-Crotonolactone) is an endogenous metabolite. 2(5H)-Furanone mimics N-acyl homoserine lactone signals, occupies the binding site of LuxR homologs, and interferes with quorum sensing-mediated gene regulation. 2(5H)-Furanone inhibits quorum sensing mediated by AHLs with different acyl chain lengths. 2(5H)-Furanone inhibits biofilm formation of environmental Aeromonas hydrophila strains on polystyrene plates. 2(5H)-Furanone suppresses spike-and-wave discharges in a rat model of generalized absence seizures and exhibits selective activity against absence seizures. 2(5H)-Furanone can be used in studies related to bacteria infections and generalized absence seizures. -
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NSC-79887
0 ImagesCat. No.: HY-117831CAS No.: 19056-78-1NSC-79887 is a nucleoside hydrolase (NH) inhibitor with activity against Bacillus anthracis. NSC-79887 is considered a good candidate inhibitor of nucleoside hydrolases for biological testing and further development. The pharmacokinetic (ADMET) prediction of NSC-79887 showed that all physicochemical parameters were within the acceptable range for human use. -
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Polyketide synthase 13-IN-2
0 ImagesCat. No.: HY-139595CAS No.: 2219338-48-2Polyketide synthase 13-IN-2 (comp 42) is a polyketide synthase 13 inhibitor against Mycobacterium tuberculosis, with an MIC of 0.25 μg/mL. -
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Sodium citrate dihydrate (Standard)
0 ImagesSynonyms: Trisodium citrate dihydrate (Standard); Citric acid trisodium salt dihydrate (Standard)Sodium citrate (dihydrate) (Standard) is the analytical standard of Sodium citrate (dihydrate). This product is intended for research and analytical applications. Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer. -
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Trigonostemon F
0 ImagesCat. No.: HY-N21516CAS No.: 1207265-02-8Trigonostemon F is a modified euphorbia diterpenoid, which is found in the roots of Trigonostemon thyrsoideum and the stems of Trigonostemon howii. Trigonostemon F inhibits the proliferation of human tumor cell lines and the growth of specific bacteria in vitro. Trigonostemon F is applicable to cancer-related research. -
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SARS-CoV-2 3CLpro-IN-4
0 ImagesCat. No.: HY-147805CAS No.: 2505241-31-4SARS-CoV-2 3CLpro-IN-4 (Compound 5g) is a SARS CoV-2 3CLpro inhibitor with antiviral, antibacterial and antifungal activities. -
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Deacetylravidomycin N-oxide
0 ImagesCat. No.: HY-N14959CAS No.: 114494-30-3Deacetylravidomycin N-oxide is an antibiotic that can be produced by Streptomyces ravidus S50905. Deacetylravidomycin N-oxide is active against Gram-positive bacteria but inactive against Gram-negative bacteria. Deacetylravidomycin N-oxide has antitumor activity against P388 leukemia and methamphetamine A fibrosarcoma. -
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Punica granatum rinds extract
0 ImagesCat. No.: HY-N19077Punica granatum rinds extract is rich in a variety of bioactive compounds, such as punicin, ellagic acid, tannins, and flavonoids, which give it powerful antioxidant, anti-inflammatory, antibacterial, and anticancer properties. -
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3,3-Dimethylacrylic acid (Standard)
0 ImagesSynonyms: 3-Methylcrotonic acid (Standard); 3-Methylbut-2-enoic acid (Standard)3,3-Dimethylacrylic acid (Standard) (3-Methylcrotonic acid (Standard)) is the analytical standard of 3,3-Dimethylacrylic acid (HY-W010611). This product is intended for research and analytical applications.3,3-Dimethylacrylic acid is an active small molecule, that can be used as drug intermediate. -
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Mtb-cyt-bd oxidase-IN-3
0 ImagesCat. No.: HY-151550Mtb-cyt-bd oxidase-IN-3 (compound 1u) is a Mycobacterium tuberculosis cytochrome bd oxidase (Mtb cyt-bd oxidase) inhibitor with an IC50 value of 0.36 μM. Mtb-cyt-bd oxidase-IN-3 inhibits the growth of Mycobacterium tuberculosis (MIC=32 μM). Mtb-cyt-bd oxidase-IN-3 can be used in tuberculosis research. -
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EGFR/InhA-IN-1
0 ImagesCat. No.: HY-179529EGFR/InhA-IN-1 (Compound 15) is an inhibitor of the anti-cancer target EGFR tyrosine kinase (1M17) (Ki = 0.05 μM) and the anti-tuberculosis target InhA enzyme (1OUZ) (Ki = 0.02 μM). EGFR/InhA-IN-1 exhibits anti-proliferative activity against A549 cells, with an IC50 of 10.38 μM. EGFR/InhA-IN-1 has inhibitory activity against Mycobacterium tuberculosis H37Rv, with a MIC of 6.25 μM. EGFR/InhA-IN-1 can be used for research on non-small cell lung cancer and Mycobacterium tuberculosis infection. -
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