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Cat. No.: HY-N21516

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Trigonostemon F

Trigonostemon F is a modified euphorbia diterpenoid, which is found in the roots of Trigonostemon thyrsoideum and the stems of Trigonostemon howii. Trigonostemon F inhibits the proliferation of human tumor cell lines and the growth of specific bacteria in vitro. Trigonostemon F is applicable to cancer-related research.

For research use only. We do not sell to patients.

CAS No.: 1207265-02-8
Formula: C₂₀H₁₆N₂O₃
Molecular Weight:332.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Trigonostemon F Chemical Structure

CAS No.: 1207265-02-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

Anti-cancerBacterial Infection

Anti-cancer

Trigonostemon F (compound 6) potently inhibits the proliferation of human tumor cell lines HL-60, SMMC-7721, A-549, MCF-7 and SW480, with IC₅₀ values ranging from 2.33 to 4.20 μM^[1].

Bacterial Infection

Trigonostemon F exhibits weak antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, MRSA 92^# and MRSA 98^#, with MIC values ranging from 12.5 to 25 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Cell Viability Determination by MTT Colorimetric Assay

Chemical Information

CAS No. 1207265-02-8
Molecular Weight 332.35
Formula C₂₀H₁₆N₂O₃
SMILES

COC1=CC=C2C(NC(/C2=C(C3=CNC4=C3C=CC=C4)\C(C)=O)=O)=C1
Structure Classification
- Alkaloids
- Indole Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Tang GH, et al. Trigohowilols A-G, degraded diterpenoids from the stems of Trigonostemon howii. Journal of natural products. 2012 Nov 26;75(11):1962-6. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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