2. Signaling Pathways
  3. GPCR/G Protein
  4. CaSR
  5. CaSR Agonist

CaSR Agonist

CaSR Agonists (9):

Cat. No. Product Name Effect Purity
  • HY-70037
    Cinacalcet
    		Agonist 99.97%
    Cinacalcet (AMG 073) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease research.
  • HY-103314
    Gadolinium chloride
    		Agonist ≥99.0%
    Gadolinium chloride is a specific calcium-sensing receptor (CaSR) agonist. Gadolinium chloride can be used for the research of cardiovascular disease.
  • HY-70037A
    Cinacalcet hydrochloride
    		Agonist 99.99%
    Cinacalcet hydrochloride (AMG-073 hydrochloride) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.
  • HY-107773
    GSK3004774
    		Agonist 98.11%
    GSK3004774 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC50 of 50 nM for human CaSR.
  • HY-122819
    Calindol hydrochloride
    		Agonist 99.88%
    Calindol hydrochloride is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an EC50 of 132 nM.
  • HY-70037S
    Cinacalcet-d3
    		Agonist
    Cinacalcet-d3 is the deuterium labeled Cinacalcet. Cinacalcet (AMG 073) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.
  • HY-P4376
    Gamma-Glu-Abu
    		Agonist
    Gamma-Glu-Abu is a potent calcium sensing receptor (CaSR) agonist.
  • HY-117851
    AC-265347
    		Agonist 99.97%
    AC-265347 is a calcium-sensing receptor (CaSR) agonist and positive allosteric modulator (ago-PAM) with the functional affinity (pKB) of 5.1. AC-265347 can be used for the research of hyperparathyroidism and related diseases.
  • HY-70037AS
    Cinacalcet-d3 hydrochloride
    		Agonist
    Cinacalcet-d3 (hydrochloride) is the deuterium labeled Cinacalcet (hydrochloride). Cinacalcet hydrochloride (AMG-073 hydrochloride) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.