Search Result
Results for "
adamanta
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
10
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-B0402
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Amantadine
Maximum Cited Publications
10 Publications Verification
1-adamantanamine; 1-Aminoadamantane
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Influenza Virus
Orthopoxvirus
SARS-CoV
Apoptosis
CDK
Bcl-2 Family
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Infection
Neurological Disease
Cancer
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Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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- HY-B0402A
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1-adamantanamine hydrochloride; 1-Adamantylamine hydrochloride; 1-Aminoadamantane hydrochloride
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Influenza Virus
Orthopoxvirus
SARS-CoV
Apoptosis
Bcl-2 Family
CDK
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Infection
Neurological Disease
Cancer
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Amantadine (1-Adamantanamine) hydrochloride is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine hydrochloride inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine hydrochloride also has anti-orthopoxvirus and anticancer activity. Amantadine hydrochloride can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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- HY-N2427
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Others
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Others
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Adamantane is a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be studied in pharmacological research to improve the lipophilicity and pharmacological properties of other active products .
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- HY-W016473
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Bacterial
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Infection
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Adamantane-carboxylic acid is a compound with inhibitory activity against microorganisms. Although its specific target has not been clearly defined, it can inhibit Gram-positive bacteria and some Gram-negative bacteria. It forms a 1-monoacylglycerol derivative through a direct reaction with glycidol, and exerts its antibacterial effect by mechanisms such as altering the permeability of the bacterial cell membrane. This compound can be used in the research of antibacterial agents in the food and cosmetic industries to reduce harmful microbial flora and extend the shelf life of products .
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- HY-W037848
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1-Aminomethyladamantane
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Drug Intermediate
Ligands for E3 Ligase
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Cancer
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Adamantan-1-ylmethanamine (1-Aminomethyladamantane) is a Hyt hydrophobic group. Adamantan-1-ylmethanamine can be used in the synthesis of ZX782 (HY-161972) .
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- HY-148430
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Cytochrome P450
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Cancer
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4-Pyridylmethyl adamantanecarboxamide (Compound 11) is an Aromatase inhibitor with an IC50 of 1.5 μM against hAromatase. 4-Pyridylmethyl adamantanecarboxamide inhibits the C17,20-lyase activity of testicular cytochrome P45017α with an IC50 of 1600 nM, and also inhibits the 17α-hydroxylase activity of this enzyme with an IC50 of 7700 nM. 4-Pyridylmethyl adamantanecarboxamide can be used in the research of prostate cancer .
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- HY-B0402S1
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1-adamantanamine-d6; 1-Aminoadamantane-d6
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Apoptosis
CDK
SARS-CoV
Bcl-2 Family
Influenza Virus
Orthopoxvirus
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Cancer
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Amantadine-d6 is the deuterium labeled Amantadine . Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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- HY-W016287
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- HY-W001578
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Biochemical Assay Reagents
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Others
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1-Adamantaneacetic acid is an aliphatic carboxylic acid that can be used as an acylating agent, commonly found in chemical synthesis .
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- HY-W001570
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Biochemical Assay Reagents
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Others
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3-Hydroxy-1-adamantanecarboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-B1044
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Kemantane; 5-Hydroxy-2-adamantanone
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Drug Derivative
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Neurological Disease
Inflammation/Immunology
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Idramantone (Kemantane, 5-Hydroxy-2-adamantanone) is an Adamantane derivative. Idramantone is an immunostimulant. Idramantone is a versatile starting material for the synthesis of various adamantine deivatives. Idramantone can be produced using P450cam monooxygenase coupled with NADH regeneration as an oxidation biocatalyst. Idramantone can be studied in research on bronchial pathology .
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- HY-B0402S
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1-adamantanamine-d15; 1-Aminoadamantane-d15
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Influenza Virus
Orthopoxvirus
SARS-CoV
Apoptosis
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Infection
Neurological Disease
Cancer
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Amantadine-d15 is the deuterium labeled Amantadine. Amantadine (1-Adamantanamine) is an antiviral agent with activity against influenza A viruses. Amantadine blocks the proton flow through the M2 ion channel (M2 proton channel of influenza A) and thus prevents the release of viral RNA into the cytoplasm of the infected cells. Amantadine is an antiparkinsonian agent .
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- HY-112026
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- HY-W000383
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Tricyclo[3.3.1.13,7]decan-2-ol
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Biochemical Assay Reagents
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Others
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2-Adamantanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W008548
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- HY-B0402B
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1-adamantanamine sulfate; 1-Aminoadamantane sulfate
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Influenza Virus
Orthopoxvirus
SARS-CoV
Apoptosis
CDK
Bcl-2 Family
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Infection
Neurological Disease
Cancer
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Amantadine (1-Adamantanamine) sulfate is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine sulfate inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine sulfate also has anti-orthopoxvirus and anticancer activity. Amantadine sulfate can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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- HY-N2427S
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Isotope-Labeled Compounds
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Others
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Adamantane-d16is the deuterium labeled Adamantane (HY-N2427). Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery .
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- HY-W016473S
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- HY-156207
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AdaGb3; Adamantyl Gb3; C2 adamantanyl Ceramide Trihexoside (d18:1/2:0)
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P-glycoprotein
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Cancer
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C2 Adamantanyl globotriaosylceramide (d18:1/2:0) (AdaGb3), a water-soluble globotriaosylceramide analog, is a bioactive sphingolipid. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) reverses MDR1-MDCK cell drug resistance. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) has high affinity for verotoxin (VT) .
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- HY-121123
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2-Aminoadamantane-2-carboxylic acid
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Aminopeptidase
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Cancer
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Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine (Ki is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC50 of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S0.5 of 10.5 .
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- HY-Y0421
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- HY-Y0531
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Tricyclo[3.3.1.1~3,7~]decan-1-ol
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Drug Intermediate
Bacterial
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Infection
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1-Adamantanol (Tricyclo[3.3.1.1~3,7~]decan-1-ol) is a hydroxylated derivative of Adamantane (HY-N2427). 1-Adamantanol serves as a substrate for regioselective hydroxylation reactions in Streptomyces strain SA8. 1-Adamantanol can form acrylate derivatives, which are used as photoresist layer materials .
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- HY-W015329
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Drug Intermediate
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Others
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3-Amino-1-adamantanol is an intermediate. 3-Amino-1-adamantanol can be used to synthesize compounds such as Vildagliptin (HY-14291) .
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- HY-161933
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PROTAC Linkers
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Cancer
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1-Adamantane-amide-C7-NH2 is the linker, which can be used for syntheisis of PROTAC GPX4 degrader-3 (HY-161930) .
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- HY-138573
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- HY-B0402R1
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1-adamantanamine in Methanol (Standard); 1-Aminoadamantane in Methanol (Standard)
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Reference Standards
Influenza Virus
Orthopoxvirus
SARS-CoV
Apoptosis
CDK
Bcl-2 Family
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Infection
Neurological Disease
Cancer
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Amantadine in Methanol (Standard) is the solution of Amantadine (Standard). This product is intended for research and analytical applications. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research [4] .
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- HY-B0402AR
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1-adamantanamine hydrochloride (Standard); 1-Adamantylamine hydrochloride (Standard); 1-Aminoadamantane hydrochloride (Standard)
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Reference Standards
Influenza Virus
Orthopoxvirus
SARS-CoV
Apoptosis
Bcl-2 Family
CDK
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Infection
Neurological Disease
Cancer
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Amantadine (hydrochloride) (Standard) is the analytical standard of Amantadine (hydrochloride). This product is intended for research and analytical applications. Amantadine (1-Adamantanamine) hydrochloride is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine hydrochloride inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine hydrochloride also has anti-orthopoxvirus and anticancer activity. Amantadine hydrochloride can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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- HY-168682
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Target Protein Ligand-Linker Conjugates
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Cancer
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Adamantane-Butyl alcohol is a selective and persistent degrader targeting the CDK8-cyclin C complex. Adamantane-Butyl alcohol is the linker for LL-K8-22 (PROTAC CDK8-cyclin C, HY-149209) and HyT .
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- HY-176390
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PROTAC Linkers
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Others
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Adamantan-C-amide-PEG2-C2-amine (Compound 8) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs, such as PROTAC β-NF-JQ1 (HY-130256) .
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- HY-W722122
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N-(1-((3r,5r,7r)-adamantan-1-yl)ethyl)hydroxylamine-d4
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Isotope-Labeled Compounds
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Others
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N-(1-(Adamantan-1-yl)ethyl)hydroxylamine-d4 (N-(1-((3r,5r,7r)-Adamantan-1-yl)ethyl)hydroxylamine-d4) is the deuterium labeled N-(1-(adamantan-1-yl)ethyl)hydroxylamine (HY-75864).
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- HY-N2427R
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Reference Standards
Others
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Others
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Adamantane (Standard) is the analytical standard of Adamantane. This product is intended for research and analytical applications. Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery .
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- HY-114747
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1-(1-Adamantyl)-3-propyl-2-thiourea
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Others
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Infection
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1-(Adamantan-1-yl)-3-propylthiourea (1-(1-Adamantyl)-3-propyl-2-thiourea) is a viricide .
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- HY-156208
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AdaGalCer(d18:1/2:0); Admantanyl galactosylceramide (d18:1/2:0); Admantanyl galCer(d18:1/2:0)
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Glycosidase
Glucosylceramide Synthase (GCS)
Glycosyltransferase
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Metabolic Disease
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C2 Adamantanyl galactosylceramide (AdaGalCer) (d18:1/2:0) is a bioactive sphingolipid. C2 Adamantanyl galactosylceramide (d18:1/2:0) stimulates glucocerebrosidase activity in vitro. C2 Adamantanyl galactosylceramide (d18:1/2:0) inhibits microsomal LacCer and Gb3 synthase, and inhibits cell sulfatide synthesis. C2 Adamantanyl galactosylceramide (d18:1/2:0) reduces glucosylceramide (GlcCer) levels in normal and lysosomal storage disease (LSD) cells. C2 Adamantanyl galactosylceramide (d18:1/2:0) acts as a substrate for A4GALT and is able to lower Gb3 levels with an IC50 concentration of 40 μM in fabry disease cells .
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- HY-W751665
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N-Benzyl-3-carboethoxy-4-piperidone hydrochloride-d3
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Isotope-Labeled Compounds
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Others
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1-(Adamantan-1-yl)ethan-1-one-d3 (N-Benzyl-3-carboethoxy-4-piperidone hydrochloride-d3) is the deuterium labeled 1-(Adamantan-1-yl)ethan-1-one (HY-W067624).
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- HY-W674002
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1-(2-Phosphaethynyl)adamantane
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Apoptosis
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1-Adamantylphosphaethyne (1-(2-Phosphaethynyl)adamantane) is a compound with potential biological activity and can be used as a catalyst in organic synthesis. 1-Adamantylphosphaethyne has shown the ability to induce cell apoptosis in compound development, which helps in anti-tumor inhibition. 1-Adamantylphosphaethyne can also be used as an efficient reaction intermediate to promote the progress of various chemical reactions.
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- HY-W653905
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1-adamantanamine hydrochloride-d15
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Isotope-Labeled Compounds
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Infection
Neurological Disease
Cancer
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Amantadine-d15 hydrochloride is deuterated labeled Amantadine. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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- HY-B0402R
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1-adamantanamine (Standard); 1-Aminoadamantane (Standard)
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Reference Standards
Influenza Virus
Orthopoxvirus
SARS-CoV
Apoptosis
CDK
Bcl-2 Family
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Infection
Neurological Disease
Cancer
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Amantadine (Standard) is the analytical standard of Amantadine. This product is intended for research and analytical applications. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research [4] .
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- HY-161974
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- HY-W074864
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Tricyclo[3.3.1.13,7]decane-1,3,5,7-tetracarboxylicacid
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MOFs
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Others
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Adamantane-1,3,5,7-tetracarboxylic acid (Tricyclo[3.3.1.13,7]decane-1,3,5,7-tetracarboxylicacid) is a metal-organic framework (MOF).
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- HY-138573S
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- HY-181469
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adamantanyl GluCer (d18:1/2:0); adamantanyl glucosylceramide (d18:1/2:0); AdaGluCer (d18:1/2:0)
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Glycosidase
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Metabolic Disease
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C2 Adamantanyl glucosylceramide (d18:1/2:0) (Adamantanyl GluCer (d18:1/2:0)) is an inhibitor of glucocerebrosidase (GCC) and LacCer synthase. At low doses, C2 Adamantanyl glucosylceramide (d18:1/2:0) increases intracellular glycolipid levels by inhibiting glucocerebrosidase. C2 Adamantanyl glucosylceramide (d18:1/2:0) alters glycolipid metabolism. C2 Adamantanyl glucosylceramide (d18:1/2:0) can be used for the research of Gaucher disease and Fabry disease .
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- HY-W097318S
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- HY-W102811
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MOFs
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Others
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1,3-Adamantanedicarboxylic acid is a metal-organic framework (MOF).
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- HY-Y0531S
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Tricyclo[3.3.1.1~3,7~]decan-1-ol-d15
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Isotope-Labeled Compounds
Drug Intermediate
Bacterial
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Infection
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1-Adamantanol-d15 (Tricyclo[3.3.1.1~3,7~]decan-1-ol-d15) is the deuterium labeled 1-Adamantanol (HY-Y0531). 1-Adamantanol (Tricyclo[3.3.1.1~3,7~]decan-1-ol) is a hydroxylated derivative of Adamantane (HY-N2427). 1-Adamantanol serves as a substrate for regioselective hydroxylation reactions in Streptomyces strain SA8. 1-Adamantanol can form acrylate derivatives, which are used as photoresist layer materials .
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- HY-W1049904
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MOFs
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Others
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5-(Adamantan-1-yl)isophthalic acid is a metal-organic framework (MOF).
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- HY-W456380
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MOFs
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Others
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4,4',4'',4'''-(Adamantane-1,3,5,7-tetrayl)tetrabenzoic acid is a metal-organic framework (MOF).
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- HY-W112396
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MOFs
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Others
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4,4',4''-((1S,3S,5S)-Adamantane-1,3,5-triyl)tribenzoic acid is a metal-organic framework (MOF).
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- HY-W1049780
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MOFs
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Others
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1,3,5,7-Tetrakis(4-(pyridin-4-yl)phenyl)adamantane is a metal-organic framework (MOF).
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- HY-170376
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E3 Ligase Ligand-Linker Conjugates
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Others
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2-(2-Aminoethoxy)ethyl 2-(adamantan-1-yl) acetate is a conjugate of an Hyt hydrophobic group and a linker, which can be used in the synthesis of SARD279 (HY-164807) .
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- HY-W809887
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MOFs
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Others
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5,5-(Adamantane-1,3-diyl)bis(2-methoxybenzoic acid) is a metal-organic framework (MOF).
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- HY-W124380
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Tricyclo(3.3.1.13,7)dec-1,3-diyldi(acetic acid)
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MOFs
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Others
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2,2'-(Adamantane-1,3-diyl)diacetic acid (Tricyclo(3.3.1.13,7)dec-1,3-diyldi(acetic acid)) is a metal-organic framework (MOF).
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| Cat. No. |
Product Name |
Type |
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- HY-W016473
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Biochemical Assay Reagents
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Adamantane-carboxylic acid is a compound with inhibitory activity against microorganisms. Although its specific target has not been clearly defined, it can inhibit Gram-positive bacteria and some Gram-negative bacteria. It forms a 1-monoacylglycerol derivative through a direct reaction with glycidol, and exerts its antibacterial effect by mechanisms such as altering the permeability of the bacterial cell membrane. This compound can be used in the research of antibacterial agents in the food and cosmetic industries to reduce harmful microbial flora and extend the shelf life of products .
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- HY-W001578
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Biochemical Assay Reagents
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1-Adamantaneacetic acid is an aliphatic carboxylic acid that can be used as an acylating agent, commonly found in chemical synthesis .
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- HY-W001570
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Biochemical Assay Reagents
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3-Hydroxy-1-adamantanecarboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W000383
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Tricyclo[3.3.1.13,7]decan-2-ol
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Biochemical Assay Reagents
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2-Adamantanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-Y0531
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Tricyclo[3.3.1.1~3,7~]decan-1-ol
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Biochemical Assay Reagents
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1-Adamantanol (Tricyclo[3.3.1.1~3,7~]decan-1-ol) is a hydroxylated derivative of Adamantane (HY-N2427). 1-Adamantanol serves as a substrate for regioselective hydroxylation reactions in Streptomyces strain SA8. 1-Adamantanol can form acrylate derivatives, which are used as photoresist layer materials .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-N2427
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- HY-N2427R
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Natural Products
Minerals
Plants
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Reference Standards
Others
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Adamantane (Standard) is the analytical standard of Adamantane. This product is intended for research and analytical applications. Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery .
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0402S1
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Amantadine-d6 is the deuterium labeled Amantadine . Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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- HY-B0402S
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Amantadine-d15 is the deuterium labeled Amantadine. Amantadine (1-Adamantanamine) is an antiviral agent with activity against influenza A viruses. Amantadine blocks the proton flow through the M2 ion channel (M2 proton channel of influenza A) and thus prevents the release of viral RNA into the cytoplasm of the infected cells. Amantadine is an antiparkinsonian agent .
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- HY-N2427S
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Adamantane-d16is the deuterium labeled Adamantane (HY-N2427). Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery .
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- HY-W016473S
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Adamantane-carboxylic Acid-d15 is the deuterium labeled Adamantane-1-carboxylic acid .
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- HY-W722122
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N-(1-(Adamantan-1-yl)ethyl)hydroxylamine-d4 (N-(1-((3r,5r,7r)-Adamantan-1-yl)ethyl)hydroxylamine-d4) is the deuterium labeled N-(1-(adamantan-1-yl)ethyl)hydroxylamine (HY-75864).
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- HY-W751665
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1-(Adamantan-1-yl)ethan-1-one-d3 (N-Benzyl-3-carboethoxy-4-piperidone hydrochloride-d3) is the deuterium labeled 1-(Adamantan-1-yl)ethan-1-one (HY-W067624).
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- HY-W653905
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Amantadine-d15 hydrochloride is deuterated labeled Amantadine. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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- HY-138573S
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N-Acetyl Adamantamine-d3 is the deuterium labeled N-Acetyl Adamantamine .
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- HY-W097318S
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1-Adamantanecarboxamide-d15 is the deuterium labeled Adamantane-1-carboxamide (HY-W097318).
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- HY-Y0531S
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1-Adamantanol-d15 (Tricyclo[3.3.1.1~3,7~]decan-1-ol-d15) is the deuterium labeled 1-Adamantanol (HY-Y0531). 1-Adamantanol (Tricyclo[3.3.1.1~3,7~]decan-1-ol) is a hydroxylated derivative of Adamantane (HY-N2427). 1-Adamantanol serves as a substrate for regioselective hydroxylation reactions in Streptomyces strain SA8. 1-Adamantanol can form acrylate derivatives, which are used as photoresist layer materials .
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