C2 Adamantanyl globotriaosylceramide (d18:1/2:0)
C2 Adamantanyl globotriaosylceramide (d18:1/2:0) (AdaGb3), a water-soluble globotriaosylceramide analog, is a bioactive sphingolipid. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) reverses MDR1-MDCK cell drug resistance. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) has high affinity for verotoxin (VT).
For research use only. We do not sell to patients.
- CAS No.: 261155-87-7
- Formula: C48H83NO18
- Molecular Weight:962.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 261155-87-7
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Molecular Weight 962.17
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Formula C48H83NO18
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SMILES
OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O[C@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO)CO)O[C@H]1OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CC45CC6CC(CC(C6)C5)C4)=O
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Synonyms
AdaGb3; Adamantyl Gb3; C2 Adamantanyl Ceramide Trihexoside (d18:1/2:0)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. De Rosa MF, et al. Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog. J Biol Chem. 2008 Feb 22;283(8):4501-11. [Content Brief]
[2]. Kamani M, et al. Adamantyl glycosphingolipids provide a new approach to the selective regulation of cellular glycosphingolipid metabolism. J Biol Chem. 2011 Jun 17;286(24):21413-26. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
C2 Adamantanyl globotriaosylceramide (d18:1/2:0) Related Classifications
HY-156207 Related Classifications
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