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Art. -Nr.: HY-W013766

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Pipemidic acid trihydrate

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Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections.

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Reinheit: 98.0%
CAS. Nr.: 72571-82-5
Formel: C₁₄H₂₃N₅O₆
Molecular Weight:357.36

Speicherung:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Pipemidic acid trihydrate Chemical Structure

CAS. Nr.: 72571-82-5

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- In Vivo
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Bioz

Biologische Aktivität

Beschreibung

Alle Antibiotic Isoform-spezifische Produkte anzeigen :

In Vitro

Pipemidic acid trihydrate is an inhibitor of DNA gyrase that is a bacterial enzyme which catalyzes the ATP-dependent negative supercoiling of DNA^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Pipemidic acid (50 mg/kg) trihydrate is absorbed well by the oral route, and the peak levels in plasma ranged from 4 to 12 μg/mL in mice, rats, dogs, monkeys^[3].
The mean lethal dose of Pipemidic acid trihydrate after a single oral dose was more than 16000 mg/kg in mice^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 72571-82-5
Appearance Solid
Molecular Weight 357.36
Formel C₁₄H₂₃N₅O₆
Color White to off-white
SMILES

CCN1C=C(C(O)=O)C(C2=CN=C(N3CCNCC3)N=C21)=O.O.O.O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Publications (1)

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Int J Biol Macromol

Reticuline isomerase AKR1B1 with aldo-keto reductase activity and detoxification function from the insect Blaps rhynchopetera. [Abstract]

2026 Mar:352:151224. PMID: 41791543

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Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
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COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
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OR (2659 KB)
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Handling Instructions (2659 KB)

Verweise

[1]. Iacovino R, et al. β-Cyclodextrin inclusion complex to improve physicochemical properties of pipemidic acid: characterization and bioactivity evaluation. Int J Mol Sci. 2013 Jun 25;14(7):13022-41. [Content Brief]

[2]. Aoyama H, et, al. Purification of Citrobacter freundii DNA gyrase and inhibition by quinolones. Antimicrob Agents Chemother. 1988 Jan;32(1):104-9. [Content Brief]

[3]. Shimizu M, et, al. Pipemidic acid: absorption, distribution, and excretion. Antimicrob Agents Chemother. 1975 Apr;7(4):441-6. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Pipemidic acid trihydrate

1 Cited Publications

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Pipemidic acid trihydrate

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Pipemidic acid trihydrate

Bioactive Compound Library Max

Bioactive Compound Library

Anti-Infection Compound Library

Antibacterial Compound Library

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High-Throughput Bioactive Compound Library

Publications Citing Use of MedChemExpress (MCE) Pipemidic acid trihydrate

Alle Antibiotic Isoform-spezifische Produkte anzeigen

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Pipemidic acid trihydrate Related Classifications

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