Bis[2-(4-hydroxyphenylthio)ethoxy]methane (Synonyms: DD-70)

Cat. No.: HY-W744923 Purity: 99.30%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Bis[2-(4-hydroxyphenylthio) ethoxy]methane (DD-70) is a Bisphenol A (BPA) replacement compound. Bis[2-(4-hydroxyphenylthio) ethoxy]methane is cytotoxic and changes the expression of genes related to xenobiotic metabolism, bile acid, and cholesterol regulation.

For research use only. We do not sell to patients.

Bis[2-(4-hydroxyphenylthio)ethoxy]methane Chemical Structure

CAS No. : 93589-69-6

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	Get quote	Estimated Time of Arrival: December 31
1 g	Get quote
5 g	Get quote

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Description

Molecular Weight

352.47

Formula

C₁₇H₂₀O₄S₂

CAS No.

93589-69-6

Appearance

Solid

Color

White to light yellow

SMILES

OC1=CC=C(C=C1)SCCOCOCCSC2=CC=C(C=C2)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (283.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8371 mL	14.1856 mL	28.3712 mL
5 mM	0.5674 mL	2.8371 mL	5.6742 mL
10 mM	0.2837 mL	1.4186 mL	2.8371 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.59%

Select Batch:

Data Sheet (267 KB) SDS (398 KB)

COA (242 KB) HNMR (175 KB) RP-HPLC (181 KB) MS (305 KB) Elemental Analysis Report (100 KB)

Handling Instructions (2659 KB)

References

[1]. Sharin T, Gyasi H, Williams KL, Crump D, O'Brien JM. Effects of two Bisphenol A replacement compounds, 1,7-bis (4-hydroxyphenylthio)-3,5-dioxaheptane and Bisphenol AF, on development and mRNA expression in chicken embryos. Ecotoxicol Environ Saf. 2021;215:112140. [Content Brief]

[2]. Sharin T, Williams KL, Chiu S, Crump D, O'Brien JM. Toxicity Screening of Bisphenol A Replacement Compounds: Cytotoxicity and mRNA Expression in Primary Hepatocytes of Chicken and Double-Crested Cormorant. Environ Toxicol Chem. 2021;40(5):1368-1378. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.8371 mL	14.1856 mL	28.3712 mL	70.9280 mL
	5 mM	0.5674 mL	2.8371 mL	5.6742 mL	14.1856 mL
	10 mM	0.2837 mL	1.4186 mL	2.8371 mL	7.0928 mL
	15 mM	0.1891 mL	0.9457 mL	1.8914 mL	4.7285 mL
	20 mM	0.1419 mL	0.7093 mL	1.4186 mL	3.5464 mL
	25 mM	0.1135 mL	0.5674 mL	1.1348 mL	2.8371 mL
	30 mM	0.0946 mL	0.4729 mL	0.9457 mL	2.3643 mL
	40 mM	0.0709 mL	0.3546 mL	0.7093 mL	1.7732 mL
	50 mM	0.0567 mL	0.2837 mL	0.5674 mL	1.4186 mL
	60 mM	0.0473 mL	0.2364 mL	0.4729 mL	1.1821 mL
	80 mM	0.0355 mL	0.1773 mL	0.3546 mL	0.8866 mL
	100 mM	0.0284 mL	0.1419 mL	0.2837 mL	0.7093 mL

Bis[2-(4-hydroxyphenylthio)ethoxy]methane Related Classifications

Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bis[2-(4-hydroxyphenylthio)ethoxy]methane93589-69-6DD-70DD70DD 70Constitutive Androstane ReceptorCARNR1I3Inhibitorinhibitorinhibit

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Bis[2-(4-hydroxyphenylthio)ethoxy]methane (Synonyms: DD-70)

Bis[2-(4-hydroxyphenylthio)ethoxy]methane Related Antibodies

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