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  6. Breviscapine

Breviscapine  (Synonyms: Breviscapinun)

Cat. No.: HY-107802 Assay: 91.03%
COA Handling Instructions

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Breviscapine is a crude flavonoid extract of Breviscapine, which is more than 85% of the active ingredient, Breviscapine. Breviscapine has a wide range of cardiovascular pharmacological activities, such as increasing blood flow, improving microcirculation, dilating blood vessels, reducing blood viscosity, promoting fibrinolysis, inhibiting platelet aggregation and thrombosis. Breviscapine has been used in the study of cerebral infarction and its sequelae, cerebral thrombosis, coronary heart disease and angina pectoris.

For research use only. We do not sell to patients.

Breviscapine Chemical Structure

Breviscapine Chemical Structure

CAS No. : 116122-36-2

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Description

Breviscapine is a crude flavonoid extract of Breviscapine, which is more than 85% of the active ingredient, Breviscapine. Breviscapine has a wide range of cardiovascular pharmacological activities, such as increasing blood flow, improving microcirculation, dilating blood vessels, reducing blood viscosity, promoting fibrinolysis, inhibiting platelet aggregation and thrombosis. Breviscapine has been used in the study of cerebral infarction and its sequelae, cerebral thrombosis, coronary heart disease and angina pectoris[1][2].

Molecular Weight

1293.34

Formula

C54H84N16O21
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

[Breviscapine]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (77.32 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7732 mL 3.8660 mL 7.7319 mL
5 mM 0.1546 mL 0.7732 mL 1.5464 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 91.03%

COA (244 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7732 mL 3.8660 mL 7.7319 mL 19.3298 mL
5 mM 0.1546 mL 0.7732 mL 1.5464 mL 3.8660 mL
10 mM 0.0773 mL 0.3866 mL 0.7732 mL 1.9330 mL
15 mM 0.0515 mL 0.2577 mL 0.5155 mL 1.2887 mL
20 mM 0.0387 mL 0.1933 mL 0.3866 mL 0.9665 mL
25 mM 0.0309 mL 0.1546 mL 0.3093 mL 0.7732 mL
30 mM 0.0258 mL 0.1289 mL 0.2577 mL 0.6443 mL
40 mM 0.0193 mL 0.0966 mL 0.1933 mL 0.4832 mL
50 mM 0.0155 mL 0.0773 mL 0.1546 mL 0.3866 mL
60 mM 0.0129 mL 0.0644 mL 0.1289 mL 0.3222 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Breviscapine116122-36-2BreviscapinunOthersInhibitorinhibitorinhibit

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