GRID1 - glutamate ionotropic receptor delta type subunit 1 Gene

Also Known as GluD1; GluD1-b

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2894

About GRID1

Cytogenetic location: 10q23.1-q23.2 Genomic coordinates (GRCh38): 10:85,599,552-86,366,795 (from NCBI)

This gene has 3 transcripts (splice variants), 329 orthologues and 17 paralogues. Biased expression in brain (RPKM 6.7), thyroid (RPKM 3.7) and 12 other tissues.

Summary

This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]

GRID1 Products (1)

mRNA Protein Name
NM_017551.3 NP_060021.1 glutamate receptor ionotropic, delta-1 precursor

GRID1 Protein Structure

ANF_receptor

ANF_receptor: Receptor family ligand binding region (40 - 397)

SBP_bac_3

SBP_bac_3: Bacterial extracellular solute-binding proteins, family 3 (446 - 805)

Lig_chan

Lig_chan: Ligand-gated ion channel (564 - 842)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1009 a.a.
Protein Preferred Names Protein Names

glutamate receptor ionotropic, delta-1

  • gluR delta-1 subunit

GRID1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GRID1 Q9ULK0 HBB Homo sapiens P68871
Anti Tag CoIP
28514442
Intra
GRID1 Q9ULK0 HBB Homo sapiens P68871
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Chromosome 17q21.31 Duplication Syndrome

  • 17q21.31 Microduplication Syndrome

  • Trisomy 17q21.31

  • Dup(17)(Q21.31)
Rett Syndrome

  • Atypical Rett Syndrome

  • RTT

  • Rett Disorder

  • Rts

  • Autism, Dementia, Ataxia, And Loss Of Purposeful Hand Use

  • Rett Syndrome, Preserved Speech Variant

  • Rett Syndrome, Atypical

  • Rett'S Disorder

  • Rett Syndrome Variant

  • Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use Syndrome

  • Cerebroatrophic Hyperammonemia

  • Rett Like Syndrome

  • Rett'S Syndrome

  • Atypical Rtt

  • Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use

  • Rett Syndrome Preserved Speech Variant

  • Rett Syndrome Zappella Variant

  • Rett Syndrome, Zappella Variant
Diaphragmatic Eventration
Schizophrenia

  • SCZD

  • Schizophrenia With Or Without An Affective Disorder

  • Schizophrenia 12

  • Schizophrenia, Susceptibility To

  • Schizophrenia-1

  • Dementia Praecox

  • Schizophrenia 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05795 GRID1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GRID1 VGNC VGNC:55986
Rattus norvegicus GRID1 RGD RGD:68366
Macaca mulatta GRID1 VGNC VGNC:73275
Felis catus GRID1 VGNC VGNC:67464
Mus musculus GRID1 MGD MGI:95812
Canis familiaris GRID1 VGNC VGNC:51898
Others GRID1 NCBI